Non-invasive assessment of coronary flow velocity reserve: A new method using transthoracic doppler echocardiography

Ya Yang*, Thomas Bartel, Holger Eggebrecht, Loredana Latina, Clemens Von Birgelen, Guido Caspari, Xinfang Wang, Raimund Erbel

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Transthoracic Doppler echocardiography (TTDE) allows noninvasive flow measurement in the distal left anterior descending artery (LAD). The feasibility of detecting coronary flow by contrast-enhanced TTDE with second harmonic technique was assessed, the coronary flow velocity reserve (CFVR) was evaluated in comparison to intracoronary Doppler flow (ICD) analysis and the CFVR after PTCA in LAD was investigated. In 77 (96 %) of 80 patients, CFVR was successfully determined with intravenous adenosine infusion. Doppler signal quality was evaluated in the first 46 patients by use of intravenous Levovist infusion and second harmonic technique. The Doppler flow was not visible in 1.patient only. CFVR determined from TTDE (2.77±0.65) was correlated closely with those from ICD (2.88±0.78) measurements (y=0.73x+0.67, r=0. 87, P<0.001). In conclusion, TTDE is a feasible method and provides reliable data on CFVR which can be used for follow-up after PTCA.

Original languageEnglish
Pages (from-to)158-163
Number of pages6
JournalJournal of Huazhong University of Science and Technology - Medical Sciences
Volume22
Issue number2
DOIs
Publication statusPublished - 1 Dec 2002
Externally publishedYes

Keywords

  • Coronary flow velocity reserve
  • Doppler echocardiography
  • Intracoronary doppler

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