Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

    Research output: Contribution to journalArticleAcademicpeer-review

    71 Citations (Scopus)
    35 Downloads (Pure)

    Abstract

    While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin
    Original languageEnglish
    Pages (from-to)2146-2162
    JournalPharmaceuticals
    Volume3
    DOIs
    Publication statusPublished - 2010

    Fingerprint

    Anti-Inflammatory Agents
    Aspirin
    Pharmaceutical Preparations
    Drug Labeling
    Edema
    Heart Failure
    Stroke
    Myocardial Infarction
    Hypertension

    Keywords

    • METIS-272073

    Cite this

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    title = "Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks",
    abstract = "While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general {"}black box{"} warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin",
    keywords = "METIS-272073",
    author = "I.L. Meek and {van de Laar}, {Mart A F J} and Vonkeman, {Harald Erwin}",
    year = "2010",
    doi = "10.3390/ph3072146",
    language = "English",
    volume = "3",
    pages = "2146--2162",
    journal = "Pharmaceuticals",
    issn = "1424-8247",
    publisher = "Multidisciplinary Digital Publishing Institute",

    }

    Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks. / Meek, I.L.; van de Laar, Mart A F J; Vonkeman, Harald Erwin.

    In: Pharmaceuticals, Vol. 3, 2010, p. 2146-2162.

    Research output: Contribution to journalArticleAcademicpeer-review

    TY - JOUR

    T1 - Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

    AU - Meek, I.L.

    AU - van de Laar, Mart A F J

    AU - Vonkeman, Harald Erwin

    PY - 2010

    Y1 - 2010

    N2 - While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin

    AB - While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin

    KW - METIS-272073

    U2 - 10.3390/ph3072146

    DO - 10.3390/ph3072146

    M3 - Article

    VL - 3

    SP - 2146

    EP - 2162

    JO - Pharmaceuticals

    JF - Pharmaceuticals

    SN - 1424-8247

    ER -