Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

I.L. Meek; Mart A F J van de Laar; Harald Erwin Vonkeman

doi:10.3390/ph3072146

Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

I.L. Meek
, Mart A F J van de Laar
, Harald Erwin Vonkeman

Research output: Contribution to journal › Article › Academic › peer-review

212 Citations (Scopus)

183 Downloads (Pure)

Abstract

While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin

Original language	English
Pages (from-to)	2146-2162
Journal	Pharmaceuticals
Volume	3
DOIs	https://doi.org/10.3390/ph3072146
Publication status	Published - 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

METIS-272073

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10.3390/ph3072146

pharmaceuticals-03-02146Final published version, 163 KB

Cite this

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abstract = "While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general {"}black box{"} warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin",

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AU - Vonkeman, Harald Erwin

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AB - While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin

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JO - Pharmaceuticals

JF - Pharmaceuticals

ER -

Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

Abstract

UN SDGs

Keywords

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