Numerical simulation of piezoelectrically agitated surface acoustic waves on microfluidic biochips

A. Gantner, R.W.H. Hoppe, D.T.P. Köster, K.G. Siebert, A. Wixforth

    Research output: Contribution to journalArticleAcademicpeer-review

    38 Citations (Scopus)

    Abstract

    Microfluidic biochips are biochemical laboratories on the microscale that are used for genotyping and sequencing in genomics, protein pro��?ling in proteomics, and cytometry in cell analysis. There are basically two classes of such biochips: active devices, where the solute transport on a network of channels on the chip surface is realized by external forces, and passive chips, where this is done using a speci��?c design of the geometry of the channel network. Among the active biochips, current interest focuses on devices whose operational principle is based on piezoelectrically driven surface acoustic waves (SAWs) generated by interdigital transducers placed on the chip surface. In this paper, we are concerned with the numerical simulation of such piezoelectrically agitated SAWs relying on a mathematical model that describes the coupling of the underlying piezoelectric and elastomechanical phenomena. Since the interdigital transducers usually operate at a ��?xed frequency, we focus on the time-harmonic case. Its variational formulation gives rise to a generalized saddle point problem for which a Fredholm alternative is shown to hold true. The discretization of the time-harmonic surface acoustic wave equations is taken care of by continuous, piecewise polynomial ��?nite elements with respect to a nested hierarchy of simplicial triangulations of the computational domain. The resulting algebraic saddle point problems are solved by blockdiagonally preconditioned iterative solvers with preconditioners of BPX-type. Numerical results are given both for a test problem documenting the performance of the iterative solution process and for a realistic SAW device illustrating the properties of SAW propagation on piezoelectric materials.
    Original languageUndefined
    Pages (from-to)145-161
    Number of pages17
    JournalComputing and visualization in science
    Volume10
    Issue numberLNCS4549/3
    DOIs
    Publication statusPublished - 2007

    Keywords

    • EWI-10963
    • IR-61895
    • METIS-241866

    Cite this