On-Chip Detection of Beads with a New Electrical Impedance Sensor

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    Abstract

    Electrical impedance measurements in microfluidic chips are used for single cell analysis. Parallel electrodes are more suited than planar ones since the electrical field distribution is more homogenous. Previous studies showed methods to make parallel electrodes by incorporating an additional layer between two glass wafers, making electrical connections to both sides needed. Also alignment of electrodes is necessary, making the fabrication of parallel electrodes more elaborate. Therefore a new, simpler fabrication method is developed for the fabrication of parallel electrode chips by incorporating a floating electrode in the microchannel just by adding one step in the fabrication process. In this way, only one side of the chip contains electrical connections. Finally, electrical impedance measurements with 3 and 6 µm polystyrene beads were done. All beads were detected and we have shown that it is possible to distinguish the two beads sizes from each other with a confidence level of 95%, based on the relative change in the electrical impedance.
    Original languageUndefined
    Title of host publicationIEEE Sensors 2010 Conference
    Place of PublicationPiscataway
    PublisherIEEE
    Pages218-221
    Number of pages4
    ISBN (Print)978-1-4244-8168-2
    DOIs
    Publication statusPublished - 2 Nov 2010
    Event9th IEEE Sensors 2010 - Hilton Waikoloa Village, Waikoloa, United States
    Duration: 1 Nov 20104 Nov 2010
    Conference number: 9

    Publication series

    NameThe 9th Annual IEEE Conference on Sensors
    PublisherIEEE

    Conference

    Conference9th IEEE Sensors 2010
    CountryUnited States
    CityWaikoloa
    Period1/11/104/11/10

    Keywords

    • IR-75994
    • EWI-19566
    • METIS-275926

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