TY - JOUR
T1 - On frail minds
T2 - addressing and assessing age-related neural decline and disease
AU - Lyreskog, David M.
PY - 2019/6/15
Y1 - 2019/6/15
N2 - The terminology surrounding frailty is used in clinical settings, and in research and development for identifying processes of, and patients in, age-related physical decline. However, a framework suitable for age-related neurodegenerative diseases needs to (1) adequately account for the effects that the processes of aging have on neural decline and disease, and (2) be helpful in identifying relevant groups of users and patients. This is becoming increasingly necessary due to emerging possibilities to detect, prevent, and treat age-related neural decline and disease. Based on a number of relevant criteria, I distinguish four groups of patients and users: robust, non-frail, pre-frail, and frail. With the four groups defined, ethical assessments can be made on an individual basis regarding which medical technologies are best suited for a person who risks, or suffers from, age-related neurodegenerative disease.
AB - The terminology surrounding frailty is used in clinical settings, and in research and development for identifying processes of, and patients in, age-related physical decline. However, a framework suitable for age-related neurodegenerative diseases needs to (1) adequately account for the effects that the processes of aging have on neural decline and disease, and (2) be helpful in identifying relevant groups of users and patients. This is becoming increasingly necessary due to emerging possibilities to detect, prevent, and treat age-related neural decline and disease. Based on a number of relevant criteria, I distinguish four groups of patients and users: robust, non-frail, pre-frail, and frail. With the four groups defined, ethical assessments can be made on an individual basis regarding which medical technologies are best suited for a person who risks, or suffers from, age-related neurodegenerative disease.
KW - Aging
KW - Frailty
KW - Neural decline
KW - Neurodegenerative disease
UR - http://www.scopus.com/inward/record.url?scp=85048461580&partnerID=8YFLogxK
U2 - 10.1007/s10433-018-0481-4
DO - 10.1007/s10433-018-0481-4
M3 - Review article
AN - SCOPUS:85048461580
SN - 1613-9372
VL - 16
SP - 205
EP - 213
JO - European journal of ageing
JF - European journal of ageing
IS - 2
ER -