On the importance of modelling organ geometry and boundary conditions for predicting three-dimensional prostate deformation

Alex Jahya (Corresponding Author), Martijn G. Schouten, Jurgen J. Fütterer, Sarthak Misra

    Research output: Contribution to journalArticleAcademicpeer-review

    10 Citations (Scopus)

    Abstract

    The use of an ultrasound probe or a needle guide during biopsy deforms both the rectal wall and the prostate, resulting in lesion motion. An accurate patient-speci﬿c ﬿nite element (FE)-based biomechanical model can be used to predict prostate deformations. In this study, an FE model of a prostate phantom is developed using magnetic resonance images, while soft-tissue elasticity is estimated in vivo using an ultrasound-based acoustic radiation force impulse imaging technique. This study con﬿rms that three-dimensional FE-predicted prostate deformation is predominantly dependent on accurate modelling of prostate geometry and boundary conditions. Upon application of various compressive displacements, our results show that a linear elastic FE model can accurately predict prostate deformations. The maximum global error between FE-predicted simulations and experimental results is 0.76 mm. Moreover, the effect of including the urethra, puboprostatic ligament and urinary bladder on prostate deformations is investigated by a sensitivity study.
    Original languageEnglish
    Pages (from-to)1-10
    Number of pages10
    JournalComputer methods in biomechanics and biomedical engineering
    Volume17
    Issue number5
    DOIs
    Publication statusPublished - 6 Jul 2012

    Keywords

    • Needle insertion
    • Magnetic resonance
    • Biopsy
    • IR-80782
    • CE-Advanced Robotics
    • Fnite element modelling
    • EWI-22020
    • ﬿nite element modelling
    • METIS-287913
    • Ultrasound
    • Computer-assisted surgical simulation

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