Organizing Multidisciplinary Care for Children with Neuromuscular Diseases

M.F. van der Velde, N. Kortbeek, N. Litvak

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The Academic Medical Center (AMC) in Amsterdam, The Netherlands, recently opened the `Children's Muscle Center Amsterdam' (CMCA). The CMCA diagnoses and treats children with neuromuscular diseases. These patients require care from a variety of clinicians. Through the establishment of the CMCA, children and their parents will generally visit the hospital only once a year, while previously they visited on average six times a year. This is a major improvement, because the hospital visits are both physically and psychologically demanding for the patients. This article describes how quantitative modelling supports the design and operations of the CMCA. First, an integer linear program is presented that selects which patients to invite for a treatment day and schedules the required combination of consultations, examinations and treatments on one day. Second, the integer linear program is used as input to a simulation to study to estimate the capacity of the CMCA, expressed in the distribution of the number patients that can be seen on one diagnosis day. Finally, a queueing model is formulated to predict the access time distributions based upon the simulation outcomes under various demand scenarios.
Original languageEnglish
Place of PublicationEnschede
PublisherUniversity of Twente
Number of pages22
Publication statusPublished - Sept 2012

Publication series

PublisherDepartment of Applied Mathematics, University of Twente
ISSN (Print)1874-4850


  • MSC-90C10
  • CR-I.6
  • MSC-60J20
  • Appointment scheduling
  • Integer linear programming
  • Health care management
  • Queueing systems
  • Patient flow


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