Outcome of endometrial cancer stage IIIA with adnexa or serosal involvement only

Jan J. Jobsen, Lambert Naudin ten Cate, Marnix L.M. Lybeert, Astrid Scholten, Elzbieta M. van der Steen-Banasik, Jacobus Adrianus Maria van der Palen, Marika C. Stenfert Kroese, Annerie Slot, Eltjo M. Schutter, Sabine Siesling

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Abstract

Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P=.0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P=.3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa
Original languageEnglish
Pages (from-to)962518-
Number of pages7
JournalObstetrics and gynecology international
Volume2011
DOIs
Publication statusPublished - 2011

Keywords

  • IR-77985
  • METIS-282243

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