Abstract
The N-hydroxyazetidines 2 and 3 are prepared startinfrom 2,3-dihydroazete 1-oxides (1a and 1b 0 by reduction with sodium borohydride and by reaction with a nucleophile, respectively. The N-thydroxyazetidines 2 and 3 can be oxidized with mercury (II) oxide to the corresponding nitrones 1 ; oxidation of the N-hydroxyazetidine 2a (unsubstituted at C-4) with two equivalent of lead tetraacetate tyields the N-tacetoxy β-lactam 4.
Original language | Undefined |
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Pages (from-to) | 1003-1006 |
Journal | Tetrahedron letters |
Volume | 23 |
Issue number | 9 |
DOIs | |
Publication status | Published - 1982 |
Keywords
- IR-68930