Oxygen saturation-dependent absorption and scattering of blood

Dirk J. Faber, Maurice C.G. Aalders, Egbert G. Mik, Brett A. Hooper, Martin J.C. van Gemert, Ton van Leeuwen

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Abstract

We report on the scattering properties of oxygenated and deoxygenated whole blood from 250 to 1000 nm. We determine the complex refractive index of oxygenated and deoxygenated hemoglobin using a Kramers-Kronig analysis and optical coherence tomography measurements. Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry.
Original languageUndefined
Pages (from-to)028102-1-028102-4
Number of pages4
JournalPhysical review letters
Volume93
Issue number2
DOIs
Publication statusPublished - 2004

Keywords

  • IR-49092
  • METIS-221095

Cite this

Faber, D. J., Aalders, M. C. G., Mik, E. G., Hooper, B. A., van Gemert, M. J. C., & van Leeuwen, T. (2004). Oxygen saturation-dependent absorption and scattering of blood. Physical review letters, 93(2), 028102-1-028102-4. https://doi.org/10.1103/PhysRevLett.93.028102
Faber, Dirk J. ; Aalders, Maurice C.G. ; Mik, Egbert G. ; Hooper, Brett A. ; van Gemert, Martin J.C. ; van Leeuwen, Ton. / Oxygen saturation-dependent absorption and scattering of blood. In: Physical review letters. 2004 ; Vol. 93, No. 2. pp. 028102-1-028102-4.
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Faber, DJ, Aalders, MCG, Mik, EG, Hooper, BA, van Gemert, MJC & van Leeuwen, T 2004, 'Oxygen saturation-dependent absorption and scattering of blood' Physical review letters, vol. 93, no. 2, pp. 028102-1-028102-4. https://doi.org/10.1103/PhysRevLett.93.028102

Oxygen saturation-dependent absorption and scattering of blood. / Faber, Dirk J.; Aalders, Maurice C.G.; Mik, Egbert G.; Hooper, Brett A.; van Gemert, Martin J.C.; van Leeuwen, Ton.

In: Physical review letters, Vol. 93, No. 2, 2004, p. 028102-1-028102-4.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Oxygen saturation-dependent absorption and scattering of blood

AU - Faber, Dirk J.

AU - Aalders, Maurice C.G.

AU - Mik, Egbert G.

AU - Hooper, Brett A.

AU - van Gemert, Martin J.C.

AU - van Leeuwen, Ton

PY - 2004

Y1 - 2004

N2 - We report on the scattering properties of oxygenated and deoxygenated whole blood from 250 to 1000 nm. We determine the complex refractive index of oxygenated and deoxygenated hemoglobin using a Kramers-Kronig analysis and optical coherence tomography measurements. Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry.

AB - We report on the scattering properties of oxygenated and deoxygenated whole blood from 250 to 1000 nm. We determine the complex refractive index of oxygenated and deoxygenated hemoglobin using a Kramers-Kronig analysis and optical coherence tomography measurements. Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry.

KW - IR-49092

KW - METIS-221095

U2 - 10.1103/PhysRevLett.93.028102

DO - 10.1103/PhysRevLett.93.028102

M3 - Article

VL - 93

SP - 028102-1-028102-4

JO - Physical review letters

JF - Physical review letters

SN - 0031-9007

IS - 2

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Faber DJ, Aalders MCG, Mik EG, Hooper BA, van Gemert MJC, van Leeuwen T. Oxygen saturation-dependent absorption and scattering of blood. Physical review letters. 2004;93(2):028102-1-028102-4. https://doi.org/10.1103/PhysRevLett.93.028102