Abstract
| Original language | Undefined |
|---|---|
| Title of host publication | Micro Total Analysis Systems |
| Editors | Tae Song Kim, Yoon-Sik Lee, Taek-Dong Chung, Noo Li Jeon, Sang-Hoon Lee, Kahp-Yang Suh, Jaebum Choo, Yong-Kweon Kim |
| Place of Publication | San Diego |
| Publisher | Chemical and Biological Society |
| Pages | 1808-1810 |
| Number of pages | 3 |
| ISBN (Print) | 978-0-9798064-2-1 |
| Publication status | Published - 1 Nov 2009 |
| Event | 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2009 - Jeju, Korea, Republic of Duration: 1 Nov 2009 → 5 Nov 2009 Conference number: 13 |
Publication series
| Name | microTAS 2009 |
|---|---|
| Publisher | Chemical and Biological Society |
| Volume | 2 |
Conference
| Conference | 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2009 |
|---|---|
| Abbreviated title | MicroTAS |
| Country | Korea, Republic of |
| City | Jeju |
| Period | 1/11/09 → 5/11/09 |
Keywords
- METIS-265248
- IR-69835
- EWI-17032
- platform
- Single cell analysis
Cite this
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Parallel single cell analysis on an integrated microfluidic platform for cell trapping, lysis and analysis. / le Gac, Severine; de Boer, Hans L.; Wijnperle, Daniël; Meuleman, W.; Carlen, Edwin; van den Berg, Albert.
Micro Total Analysis Systems. ed. / Tae Song Kim; Yoon-Sik Lee; Taek-Dong Chung; Noo Li Jeon; Sang-Hoon Lee; Kahp-Yang Suh; Jaebum Choo; Yong-Kweon Kim. San Diego : Chemical and Biological Society, 2009. p. 1808-1810 (microTAS 2009; Vol. 2).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
TY - GEN
T1 - Parallel single cell analysis on an integrated microfluidic platform for cell trapping, lysis and analysis
AU - le Gac, Severine
AU - de Boer, Hans L.
AU - Wijnperle, Daniël
AU - Meuleman, W.
AU - Carlen, Edwin
AU - van den Berg, Albert
PY - 2009/11/1
Y1 - 2009/11/1
N2 - We report here a novel and easily scalable microfluidic platform for the parallel analysis of hundreds of individual cells, with controlled single cell trapping, followed by their lysis and subsequent retrieval of the cellular content for on-chip analysis. The device consists of a main channel and an array of shallow side channels connected to the main channel via trapping structures. Cells are individually captured in dam structures by application of a negative pressure from an outlet reservoir, lyzed on site and the cellular content controllably extracted and transported in the individual side channels for on-chip analysis.
AB - We report here a novel and easily scalable microfluidic platform for the parallel analysis of hundreds of individual cells, with controlled single cell trapping, followed by their lysis and subsequent retrieval of the cellular content for on-chip analysis. The device consists of a main channel and an array of shallow side channels connected to the main channel via trapping structures. Cells are individually captured in dam structures by application of a negative pressure from an outlet reservoir, lyzed on site and the cellular content controllably extracted and transported in the individual side channels for on-chip analysis.
KW - METIS-265248
KW - IR-69835
KW - EWI-17032
KW - platform
KW - Single cell analysis
M3 - Conference contribution
SN - 978-0-9798064-2-1
T3 - microTAS 2009
SP - 1808
EP - 1810
BT - Micro Total Analysis Systems
A2 - Kim, Tae Song
A2 - Lee, Yoon-Sik
A2 - Chung, Taek-Dong
A2 - Jeon, Noo Li
A2 - Lee, Sang-Hoon
A2 - Suh, Kahp-Yang
A2 - Choo, Jaebum
A2 - Kim, Yong-Kweon
PB - Chemical and Biological Society
CY - San Diego
ER -