Parkinsonian pattern transduction by GPi

Tjitske Heida, N. Beaujean

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    Abstract

    It is hypothesised that Parkinson’s disease is explained as a change in the pattern of synchronisation of discharges between neurons within the subthalamo-pallidal-thalamo-cortical circuit. By simulating a single GPi neuron receiving non-synchronous and oscillatory inputs the conditions required for the generation of normal and Parkinsonian patterns are determined.
    Original languageUndefined
    Title of host publicationAnnual symposium of the IEEE-EMBS Benelux Chapter
    Place of PublicationThe Netherlands
    PublisherUniversity of Twente
    Pages70
    Number of pages1
    ISBN (Print)978-90-365-2933-4
    Publication statusPublished - 24 Nov 2009
    Event4th Annual Symposium of the Benelux Chapter of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBS Benelux) 2009 - University of Twente, Enschede, Netherlands
    Duration: 9 Nov 200910 Nov 2009
    Conference number: 4

    Publication series

    NameAnnual Symposium of the IEEE/EMBS Benelux Chapter
    PublisherUniversity of Twente
    Volume4th Annual Symposium of the IEEE/EMBS Benelux Chapter

    Conference

    Conference4th Annual Symposium of the Benelux Chapter of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBS Benelux) 2009
    Country/TerritoryNetherlands
    CityEnschede
    Period9/11/0910/11/09

    Keywords

    • METIS-268933
    • EWI-17371
    • BSS-Electrical Neurostimulation
    • IR-70363

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