TY - JOUR
T1 - Path-length-resolved measurements of multiple scattered photons in static and dynamic turbid media using phase-modulated low-coherence interferometry
AU - Varghese, Babu
AU - Rajan, Vinayakrishnan
AU - Van Leeuwen, Ton G.
AU - Steenbergen, Wiendelt
PY - 2007/3/1
Y1 - 2007/3/1
N2 - In optical Doppler measurements, the path length of the light is unknown. To facilitate quantitative measurements, we develop a phase-modulated Mach-Zehnder interferometer with separate fibers for illumination and detection. With this setup, path-length-resolved dynamic light scattering measurements of multiple scattered light in static and dynamic turbid media are performed. Optical path length distributions spanning a range from 0 to11mm are measured from the area under the phase modulation peak around the modulation frequency in the power spectrum. A Doppler-broadened phase modulation interference peak is observed that shows an increase in the average Doppler shift with optical path length, independent of absorption. Validation of the estimated path length distributions is done by measuring their deformation for increasing absorption and comparing these observations with predictions based on Lambert-Beer's law.
AB - In optical Doppler measurements, the path length of the light is unknown. To facilitate quantitative measurements, we develop a phase-modulated Mach-Zehnder interferometer with separate fibers for illumination and detection. With this setup, path-length-resolved dynamic light scattering measurements of multiple scattered light in static and dynamic turbid media are performed. Optical path length distributions spanning a range from 0 to11mm are measured from the area under the phase modulation peak around the modulation frequency in the power spectrum. A Doppler-broadened phase modulation interference peak is observed that shows an increase in the average Doppler shift with optical path length, independent of absorption. Validation of the estimated path length distributions is done by measuring their deformation for increasing absorption and comparing these observations with predictions based on Lambert-Beer's law.
KW - Doppler
KW - Light
KW - Mach-Zehnder interferometer
KW - Phase modulation
KW - Turbid media
UR - http://www.scopus.com/inward/record.url?scp=34250662158&partnerID=8YFLogxK
U2 - 10.1117/1.2714795
DO - 10.1117/1.2714795
M3 - Article
C2 - 17477735
AN - SCOPUS:34250662158
SN - 1083-3668
VL - 12
JO - Journal of biomedical optics
JF - Journal of biomedical optics
IS - 2
M1 - 024020
ER -