Path-length-resolved optical Doppler perfusion monitoring

Babu Varghese; Vinayakrishnan Rajan; Ton van Leeuwen; Wiendelt Steenbergen

doi:10.1117/1.2823141

Path-length-resolved optical Doppler perfusion monitoring

Babu Varghese, Vinayakrishnan Rajan, Ton van Leeuwen, Wiendelt Steenbergen

Research output: Contribution to journal › Article › Academic › peer-review

123 Downloads (Pure)

Abstract

We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor

Original language	Undefined
Pages (from-to)	060508-1-060508-3
Number of pages	3
Journal	Journal of biomedical optics
Volume	12
Issue number	6
DOIs	https://doi.org/10.1117/1.2823141
Publication status	Published - 2007

Keywords

IR-74796
METIS-243927

Access to Document

10.1117/1.2823141

path-length

Cite this

@article{f7db6a1b4b5c42e3b349c61037760c80,

title = "Path-length-resolved optical Doppler perfusion monitoring",

abstract = "We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor",

keywords = "IR-74796, METIS-243927",

author = "Babu Varghese and Vinayakrishnan Rajan and {van Leeuwen}, Ton and Wiendelt Steenbergen",

note = " Open access article ",

year = "2007",

doi = "10.1117/1.2823141",

language = "Undefined",

volume = "12",

pages = "060508--1--060508--3",

journal = "Journal of biomedical optics",

issn = "1083-3668",

publisher = "SPIE",

number = "6",

}

TY - JOUR

T1 - Path-length-resolved optical Doppler perfusion monitoring

AU - Varghese, Babu

AU - Rajan, Vinayakrishnan

AU - van Leeuwen, Ton

AU - Steenbergen, Wiendelt

N1 - Open access article

PY - 2007

Y1 - 2007

N2 - We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor

AB - We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor

KW - IR-74796

KW - METIS-243927

U2 - 10.1117/1.2823141

DO - 10.1117/1.2823141

M3 - Article

SN - 1083-3668

VL - 12

SP - 060508-1-060508-3

JO - Journal of biomedical optics

JF - Journal of biomedical optics

IS - 6

ER -