Path-length-resolved optical Doppler perfusion monitoring

Babu Varghese, Vinayakrishnan Rajan, Ton van Leeuwen, Wiendelt Steenbergen

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor
Original languageUndefined
Pages (from-to)060508-1-060508-3
Number of pages3
JournalJournal of biomedical optics
Volume12
Issue number6
DOIs
Publication statusPublished - 2007

Keywords

  • IR-74796
  • METIS-243927

Cite this

Varghese, Babu ; Rajan, Vinayakrishnan ; van Leeuwen, Ton ; Steenbergen, Wiendelt. / Path-length-resolved optical Doppler perfusion monitoring. In: Journal of biomedical optics. 2007 ; Vol. 12, No. 6. pp. 060508-1-060508-3.
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author = "Babu Varghese and Vinayakrishnan Rajan and {van Leeuwen}, Ton and Wiendelt Steenbergen",
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Path-length-resolved optical Doppler perfusion monitoring. / Varghese, Babu; Rajan, Vinayakrishnan; van Leeuwen, Ton; Steenbergen, Wiendelt.

In: Journal of biomedical optics, Vol. 12, No. 6, 2007, p. 060508-1-060508-3.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Path-length-resolved optical Doppler perfusion monitoring

AU - Varghese, Babu

AU - Rajan, Vinayakrishnan

AU - van Leeuwen, Ton

AU - Steenbergen, Wiendelt

N1 - Open access article

PY - 2007

Y1 - 2007

N2 - We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor

AB - We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor

KW - IR-74796

KW - METIS-243927

U2 - 10.1117/1.2823141

DO - 10.1117/1.2823141

M3 - Article

VL - 12

SP - 060508-1-060508-3

JO - Journal of biomedical optics

JF - Journal of biomedical optics

SN - 1083-3668

IS - 6

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