TY - JOUR
T1 - Pattern of Ipsilateral Breast Tumor Recurrence After Breast-Conserving Therapy
AU - Jobsen, Jan
AU - van der Palen, Job
AU - Riemersma, Sietske
AU - Heijmans, Harald
AU - Ong, Francisca
AU - Struikmans, Henk
PY - 2014
Y1 - 2014
N2 - The rate of ipsilateral breast tumor recurrence (IBTR) in breast cancer after breast-conserving therapy was analyzed. We demonstrate that after 12 years' follow-up, there is an especially high recurrence rate for women ≤40 years old. For women ≤40 years old, the absence of adjuvant systemic therapy and the presence of lymph vascular space invasion (LVSI) are associated with a higher rate of IBTR. For women >40 years old, the presence of LVSI and lobular carcinoma in situ are prognostic factors for IBTR.
AB - The rate of ipsilateral breast tumor recurrence (IBTR) in breast cancer after breast-conserving therapy was analyzed. We demonstrate that after 12 years' follow-up, there is an especially high recurrence rate for women ≤40 years old. For women ≤40 years old, the absence of adjuvant systemic therapy and the presence of lymph vascular space invasion (LVSI) are associated with a higher rate of IBTR. For women >40 years old, the presence of LVSI and lobular carcinoma in situ are prognostic factors for IBTR.
U2 - 10.1016/j.ijrobp.2014.04.039
DO - 10.1016/j.ijrobp.2014.04.039
M3 - Article
VL - 89
SP - 1006
EP - 1014
JO - International journal of radiation: Oncology - Biology - Physics
JF - International journal of radiation: Oncology - Biology - Physics
SN - 0360-3016
IS - 5
ER -