A simple experiment based on exclusion of Pd nanoclusters was used to identify the true catalytic species in cluster-catalyzed Heck cross-couplings. A special reactor was used in which two compartments are separated by a nanoporous membrane that allows the passage of Pd atoms and ions but not of Pd nanoclusters. The results show that the real catalysts in the Heck coupling of n-butyl acrylate with iodobenzene are species leached from the Pd nanoclusters.
- Heck reaction
- homogeneous catalysis
Thathagar, M. B., ten Elshof, J. E., & Rothenberg, G. (2006). Pd nanoclusters in C-C coupling reaction: proof of leaching. Angewandte Chemie (international edition), 45(18), 2886-2890. https://doi.org/10.1002/anie.200504321