Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds

F.P.W. Melchels, Dirk W. Grijpma, Jan Feijen

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In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.
Original languageUndefined
Pages (from-to)e98-e100
JournalJournal of controlled release
Issue number2
Publication statusPublished - 2006


  • METIS-245520
  • IR-71114
  • EC Grant Agreement nr.: FP6/500465

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