Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Radiofrequency ablation (RFA) is a widely used treatment method for unresectable malignant tumors. In percutaneous RFA, the tumor recurrence rate is high due to incomplete ablation. Feedback from the imaging system during the RFA procedure is vital in reducing the tumor recurrence. We propose the use of photoacoustic (PA) imaging, integrated with an ultrasound (US) system to monitor the RFA procedure. The imaging system consists of a US system with a linear array and a pulsed laser illumination. We study the PA assisted RFA device guidance to an anomalous target embedded inside a chicken breast tissue. We compare both US and PA images to highlight the advantage of using the proposed method. Further, we image an ablated ex vivo bovine liver sample using the system. The result shows a drop in PA intensity from the ablated region compared to normal tissue. Our preliminary study shows that PA imaging is a potential modality for RFA procedures.
Original languageEnglish
Title of host publicationProceedings Opto-Acoustic Methods and Applications in Biophotonics IV
EditorsVasilis Ntziachristos, Roger Zemp
PublisherSPIE
Number of pages3
Volume11077
ISBN (Electronic)9781510628472
DOIs
Publication statusPublished - 20 Jul 2019
EventEuropean Conferences on Biomedical Optics 2019 - ICM─International Congress Center, Munich, Germany
Duration: 23 Jun 201927 Jun 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11077
ISSN (Print)1605-7422

Conference

ConferenceEuropean Conferences on Biomedical Optics 2019
CountryGermany
CityMunich
Period23/06/1927/06/19

Fingerprint

Photoacoustic effect
Infrared imaging
Ablation
lesions
ablation
Hot Temperature
Equipment and Supplies
Tumors
tumors
Ultrasonics
Imaging systems
Recurrence
Neoplasms
Lighting
Tissue
Imaging techniques
chickens
Chickens
Breast
Lasers

Keywords

  • Bovine liver
  • Ex vivo
  • Photoacoustic Imaging
  • Radiofrequency ablation
  • Real-time guidance
  • Ultrasound

Cite this

Francis, K. J., & Manohar, S. (2019). Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. In V. Ntziachristos, & R. Zemp (Eds.), Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV (Vol. 11077). [1107715] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11077). SPIE. https://doi.org/10.1117/12.2526999
Francis, K. J. ; Manohar, Srirang . / Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. editor / Vasilis Ntziachristos ; Roger Zemp. Vol. 11077 SPIE, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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abstract = "Radiofrequency ablation (RFA) is a widely used treatment method for unresectable malignant tumors. In percutaneous RFA, the tumor recurrence rate is high due to incomplete ablation. Feedback from the imaging system during the RFA procedure is vital in reducing the tumor recurrence. We propose the use of photoacoustic (PA) imaging, integrated with an ultrasound (US) system to monitor the RFA procedure. The imaging system consists of a US system with a linear array and a pulsed laser illumination. We study the PA assisted RFA device guidance to an anomalous target embedded inside a chicken breast tissue. We compare both US and PA images to highlight the advantage of using the proposed method. Further, we image an ablated ex vivo bovine liver sample using the system. The result shows a drop in PA intensity from the ablated region compared to normal tissue. Our preliminary study shows that PA imaging is a potential modality for RFA procedures.",
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Francis, KJ & Manohar, S 2019, Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. in V Ntziachristos & R Zemp (eds), Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. vol. 11077, 1107715, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11077, SPIE, European Conferences on Biomedical Optics 2019, Munich, Germany, 23/06/19. https://doi.org/10.1117/12.2526999

Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. / Francis, K. J.; Manohar, Srirang .

Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. ed. / Vasilis Ntziachristos; Roger Zemp. Vol. 11077 SPIE, 2019. 1107715 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11077).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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Francis KJ, Manohar S. Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. In Ntziachristos V, Zemp R, editors, Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. Vol. 11077. SPIE. 2019. 1107715. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2526999