Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Radiofrequency ablation (RFA) is a widely used treatment method for unresectable malignant tumors. In percutaneous RFA, the tumor recurrence rate is high due to incomplete ablation. Feedback from the imaging system during the RFA procedure is vital in reducing the tumor recurrence. We propose the use of photoacoustic (PA) imaging, integrated with an ultrasound (US) system to monitor the RFA procedure. The imaging system consists of a US system with a linear array and a pulsed laser illumination. We study the PA assisted RFA device guidance to an anomalous target embedded inside a chicken breast tissue. We compare both US and PA images to highlight the advantage of using the proposed method. Further, we image an ablated ex vivo bovine liver sample using the system. The result shows a drop in PA intensity from the ablated region compared to normal tissue. Our preliminary study shows that PA imaging is a potential modality for RFA procedures.
Original languageEnglish
Title of host publicationProceedings Opto-Acoustic Methods and Applications in Biophotonics IV
PublisherSPIE
Number of pages3
Volume11077
DOIs
Publication statusPublished - 20 Jul 2019
EventEuropean Conferences on Biomedical Optics 2019 - ICM─International Congress Center, Munich, Germany
Duration: 23 Jun 201927 Jun 2019

Conference

ConferenceEuropean Conferences on Biomedical Optics 2019
CountryGermany
CityMunich
Period23/06/1927/06/19

Fingerprint

lesions
ablation
tumors
chickens
linear arrays
liver
breast
pulsed lasers
illumination

Cite this

Francis, K. J., & Manohar, S. (2019). Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. In Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV (Vol. 11077). [1107715] SPIE. https://doi.org/10.1117/12.2526999
Francis, K. J. ; Manohar, Srirang . / Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. Vol. 11077 SPIE, 2019.
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abstract = "Radiofrequency ablation (RFA) is a widely used treatment method for unresectable malignant tumors. In percutaneous RFA, the tumor recurrence rate is high due to incomplete ablation. Feedback from the imaging system during the RFA procedure is vital in reducing the tumor recurrence. We propose the use of photoacoustic (PA) imaging, integrated with an ultrasound (US) system to monitor the RFA procedure. The imaging system consists of a US system with a linear array and a pulsed laser illumination. We study the PA assisted RFA device guidance to an anomalous target embedded inside a chicken breast tissue. We compare both US and PA images to highlight the advantage of using the proposed method. Further, we image an ablated ex vivo bovine liver sample using the system. The result shows a drop in PA intensity from the ablated region compared to normal tissue. Our preliminary study shows that PA imaging is a potential modality for RFA procedures.",
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Francis, KJ & Manohar, S 2019, Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. in Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. vol. 11077, 1107715, SPIE, European Conferences on Biomedical Optics 2019, Munich, Germany, 23/06/19. https://doi.org/10.1117/12.2526999

Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. / Francis, K. J.; Manohar, Srirang .

Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. Vol. 11077 SPIE, 2019. 1107715.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

TY - GEN

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Francis KJ, Manohar S. Photoacoustic assisted device guidance and thermal lesion imaging for radiofrequency ablation. In Proceedings Opto-Acoustic Methods and Applications in Biophotonics IV. Vol. 11077. SPIE. 2019. 1107715 https://doi.org/10.1117/12.2526999