Photoacoustic-guided focused ultrasound (PAFUSion) for identifying reflection artifacts in photoacoustic imaging

M. Kuniyil Ajith Singh, Wiendelt Steenbergen

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)
12 Downloads (Pure)

Abstract

Influence of acoustic inhomogeneities and resulting reflection artifacts is an important problem in reflection-mode photoacoustic imaging. Absorption of light by skin and superficial optical absorbers will generate photoacoustic transients, which traverse into the tissue and get reflected from structures having different acoustic impedance. These reflected photoacoustic signals, when reconstructed, may appear in the region of interest, which causes difficulties in image interpretation. We propose a novel method to identify and potentially eliminate reflection artifacts in photoacoustic images using photoacoustic-guided focused ultrasound [PAFUSion]. Our method uses focused ultrasound pulses to mimic the wave field produced by photoacoustic sources and thus provides a way to identify reflection artifacts in clinical combined photoacoustic and pulse-echo ultrasound. Simulation and phantom results are presented to demonstrate the validity and impact of this method. Results show that PAFUSion can identify reflections in photoacoustic images and thus envisages potential for improving photoacoustic imaging of acoustically inhomogeneous tissue.

Original languageEnglish
Pages (from-to)123-131
Number of pages9
JournalPhotoacoustics
Volume3
Issue number4
DOIs
Publication statusPublished - 1 Dec 2015

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Artifacts
artifacts
Acoustics
Skin Absorption
Electric Impedance
acoustic impedance
Light
pulses
absorbers
echoes
inhomogeneity
acoustics
causes
simulation

Keywords

  • Contrast
  • Epi-photoacoustic
  • Imaging depth
  • Photoacoustic
  • Ultrasound

Cite this

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abstract = "Influence of acoustic inhomogeneities and resulting reflection artifacts is an important problem in reflection-mode photoacoustic imaging. Absorption of light by skin and superficial optical absorbers will generate photoacoustic transients, which traverse into the tissue and get reflected from structures having different acoustic impedance. These reflected photoacoustic signals, when reconstructed, may appear in the region of interest, which causes difficulties in image interpretation. We propose a novel method to identify and potentially eliminate reflection artifacts in photoacoustic images using photoacoustic-guided focused ultrasound [PAFUSion]. Our method uses focused ultrasound pulses to mimic the wave field produced by photoacoustic sources and thus provides a way to identify reflection artifacts in clinical combined photoacoustic and pulse-echo ultrasound. Simulation and phantom results are presented to demonstrate the validity and impact of this method. Results show that PAFUSion can identify reflections in photoacoustic images and thus envisages potential for improving photoacoustic imaging of acoustically inhomogeneous tissue.",
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Photoacoustic-guided focused ultrasound (PAFUSion) for identifying reflection artifacts in photoacoustic imaging. / Kuniyil Ajith Singh, M.; Steenbergen, Wiendelt.

In: Photoacoustics, Vol. 3, No. 4, 01.12.2015, p. 123-131.

Research output: Contribution to journalArticleAcademicpeer-review

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