Photoacoustic imaging of blood perfusion in tissue and phantoms

Magdalena C. Pilatou; Roy G.M. Kolkman; Erwin Hondebrink; René Alexander Bolt; Frits F.M. de Mul

doi:10.1117/12.429318

Photoacoustic imaging of blood perfusion in tissue and phantoms

Magdalena C. Pilatou, Roy G.M. Kolkman, Erwin Hondebrink, René Alexander Bolt, Frits F.M. de Mul

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

4 Citations (Scopus)

7 Downloads (Pure)

Abstract

To localize and monitor the blood content in tissue we developed a very sensitive photo-acoustical detector. PVDF has been used as piezo-electric material. In this detector also fibers for the illumination of the sample are integrated. Resolution is about 20 (m in depth and about 50-100 m laterally). We use 532 nm light. We will show how photoacoustics can be used for measuring the thickness of tissue above bone. We will also report measurements on tissue phantoms: e.g. a vessel delta from the epigastric artery branching of a Wistar rat, filled with an artificial blood-resembling absorber. The measurements have been carried out on phantoms containing vessels at several depths. Signal processing was enhanced by Fourier processing of the data.

Original language	English
Title of host publication	Biomedical Optoacoustics II (BIOS 2001)
Subtitle of host publication	International Symposium on Biomedical Optics, 20-26 January 2001, San Jose, CA, USA
Editors	Alexander A. Oraevsky
Publisher	SPIE
Pages	28-33
Number of pages	6
ISBN (Print)	0-8194-3934-7
DOIs	https://doi.org/10.1117/12.429318
Publication status	Published - 20 Jan 2001
Event	SPIE International Symposium on Biomedical Optics, BIOS 2001 - San Jose, United States Duration: 20 Jan 2001 → 26 Jan 2001

Publication series

Name	Proceedings of SPIE
Publisher	SPIE
Volume	4256

Conference

Conference	SPIE International Symposium on Biomedical Optics, BIOS 2001
Abbreviated title	BIOS
Country/Territory	United States
City	San Jose
Period	20/01/01 → 26/01/01

Keywords

Photoacoustics
Piezoelectric transducers
Tissue
Blood
Imaging

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10.1117/12.429318

Cite this

Pilatou, M. C., Kolkman, R. G. M., Hondebrink, E., Bolt, R. A., & de Mul, F. F. M. (2001). Photoacoustic imaging of blood perfusion in tissue and phantoms. In A. A. Oraevsky (Ed.), Biomedical Optoacoustics II (BIOS 2001): International Symposium on Biomedical Optics, 20-26 January 2001, San Jose, CA, USA (pp. 28-33). (Proceedings of SPIE; Vol. 4256). SPIE. https://doi.org/10.1117/12.429318

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title = "Photoacoustic imaging of blood perfusion in tissue and phantoms",

abstract = "To localize and monitor the blood content in tissue we developed a very sensitive photo-acoustical detector. PVDF has been used as piezo-electric material. In this detector also fibers for the illumination of the sample are integrated. Resolution is about 20 (m in depth and about 50-100 m laterally). We use 532 nm light. We will show how photoacoustics can be used for measuring the thickness of tissue above bone. We will also report measurements on tissue phantoms: e.g. a vessel delta from the epigastric artery branching of a Wistar rat, filled with an artificial blood-resembling absorber. The measurements have been carried out on phantoms containing vessels at several depths. Signal processing was enhanced by Fourier processing of the data.",

keywords = "Photoacoustics, Piezoelectric transducers, Tissue, Blood, Imaging",

author = "Pilatou, {Magdalena C.} and Kolkman, {Roy G.M.} and Erwin Hondebrink and Bolt, {Ren{\'e} Alexander} and {de Mul}, {Frits F.M.}",

year = "2001",

month = jan,

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doi = "10.1117/12.429318",

language = "English",

isbn = "0-8194-3934-7",

series = "Proceedings of SPIE",

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editor = "Oraevsky, {Alexander A.}",

booktitle = "Biomedical Optoacoustics II (BIOS 2001)",

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Pilatou, MC, Kolkman, RGM, Hondebrink, E, Bolt, RA & de Mul, FFM 2001, Photoacoustic imaging of blood perfusion in tissue and phantoms. in AA Oraevsky (ed.), Biomedical Optoacoustics II (BIOS 2001): International Symposium on Biomedical Optics, 20-26 January 2001, San Jose, CA, USA. Proceedings of SPIE, vol. 4256, SPIE, pp. 28-33, SPIE International Symposium on Biomedical Optics, BIOS 2001, San Jose, California, United States, 20/01/01. https://doi.org/10.1117/12.429318

Photoacoustic imaging of blood perfusion in tissue and phantoms. / Pilatou, Magdalena C.; Kolkman, Roy G.M.; Hondebrink, Erwin et al.
Biomedical Optoacoustics II (BIOS 2001): International Symposium on Biomedical Optics, 20-26 January 2001, San Jose, CA, USA. ed. / Alexander A. Oraevsky. SPIE, 2001. p. 28-33 (Proceedings of SPIE; Vol. 4256).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Photoacoustic imaging of blood perfusion in tissue and phantoms

AU - Pilatou, Magdalena C.

AU - Kolkman, Roy G.M.

AU - Hondebrink, Erwin

AU - Bolt, René Alexander

AU - de Mul, Frits F.M.

PY - 2001/1/20

Y1 - 2001/1/20

N2 - To localize and monitor the blood content in tissue we developed a very sensitive photo-acoustical detector. PVDF has been used as piezo-electric material. In this detector also fibers for the illumination of the sample are integrated. Resolution is about 20 (m in depth and about 50-100 m laterally). We use 532 nm light. We will show how photoacoustics can be used for measuring the thickness of tissue above bone. We will also report measurements on tissue phantoms: e.g. a vessel delta from the epigastric artery branching of a Wistar rat, filled with an artificial blood-resembling absorber. The measurements have been carried out on phantoms containing vessels at several depths. Signal processing was enhanced by Fourier processing of the data.

AB - To localize and monitor the blood content in tissue we developed a very sensitive photo-acoustical detector. PVDF has been used as piezo-electric material. In this detector also fibers for the illumination of the sample are integrated. Resolution is about 20 (m in depth and about 50-100 m laterally). We use 532 nm light. We will show how photoacoustics can be used for measuring the thickness of tissue above bone. We will also report measurements on tissue phantoms: e.g. a vessel delta from the epigastric artery branching of a Wistar rat, filled with an artificial blood-resembling absorber. The measurements have been carried out on phantoms containing vessels at several depths. Signal processing was enhanced by Fourier processing of the data.

KW - Photoacoustics

KW - Piezoelectric transducers

KW - Tissue

KW - Blood

KW - Imaging

U2 - 10.1117/12.429318

DO - 10.1117/12.429318

M3 - Conference contribution

SN - 0-8194-3934-7

T3 - Proceedings of SPIE

SP - 28

EP - 33

BT - Biomedical Optoacoustics II (BIOS 2001)

A2 - Oraevsky, Alexander A.

PB - SPIE

T2 - SPIE International Symposium on Biomedical Optics, BIOS 2001

Y2 - 20 January 2001 through 26 January 2001

ER -

Photoacoustic imaging of blood perfusion in tissue and phantoms

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Keywords

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