Photoacoustic Imaging of Valves in Superficial Veins

R.G.M. Kolkman, Nienke Bosschaart, Ben Kok, Ton van Leeuwen, Wiendelt Steenbergen

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
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Background and Objectives: In intravenous access to veins there is a risk of puncturing venous valves or blocking of the catheter by the valves. Therefore, we have investigated whether and how photoacoustic imaging (PAI), which visualizes the lumen of blood vessels, can be used to detect these valves. - Study Design/Materials and Methods: Venous valves in superficial veins on the dorsal side of the hand of human volunteers were located by palpation and visual inspection. Next, this location was imaged using PAI. - Results: In 16 of 21 human volunteers venous valves that were found by palpation could be observed by PAI as local discontinuities in the imaged vessel. From these images, four characteristic features by which venous valves can be recognized in photoacoustic images were identified. - Conclusions: PAI has the potential to be applied in the detection of venous valves. Lasers Surg. Med. 38:740-744, 2006.
Original languageEnglish
Pages (from-to)740-744
Number of pages5
JournalLasers in surgery and medicine
Issue number8
Publication statusPublished - 2006


  • Ultrasound
  • vascular
  • IR-72072
  • optoacoustic
  • Blood vessel
  • METIS-233954


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