Transurethral laser coagulation of the prostate is a recent development in the treatment of benign prostatic hyperplasia (BPH). At present many devices are available to bring laser light energy into the prostate, but their method of action differs. In this study, the optical and thermal characteristics of the various commercially available devices for treating BPH, using transurethrally delivered Nd:YAG laser light, were evaluated. To calculate the optimal parameters for each deliveiy system, the created tissue effect was dynamically modeled. Optically the devices were evaluated using by measuring the three dimensional irradiance distribution in a water environment. The thermal behavior of the devices was studied by a specially developed thermal imaging technique. The optical and thermal characteristics of the devices together with optical and thermal parameters of prostatic tissue were used as an input for a theoretical model to predict the extent oflaser induced permanent damage and thus the effect ofthe device. Results show the influence the beam profile, spot size and secondary reflections of the different devices and their consequence for the therapeutic effect. Measuring the physical characteristics of each laser prostatectomy device and modeling its therapeutic effect, will contribute to obtain an optimal dosimetry with best fitted parameters for each individual device.
|Number of pages||9|
|Journal||Proceedings of SPIE - the international society for optical engineering|
|Publication status||Published - 2 May 1994|
|Event||Lasers in Urology 1994 - Los Angeles, United States|
Duration: 23 Jan 1994 → 29 Jan 1994