Piperazine-containing polymer brush layer as supported base catalyst in a glass microreactor

Rajesh Munirathinam, Jurriaan Huskens, Willem Verboom

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
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The covalent attachment of piperazine onto the inner walls of a microreactor using glycidyl methacrylate polymer brushes has been demonstrated. The piperazine-containing polymer brushes were first grown on a flat silicon oxide surface and were characterized by contact angle, Fourier transform infrared (FT-IR), ellipsometry, and X-ray photoelectron spectroscopy (XPS). The applicability of the catalytic polymer brushes in a microreactor was demonstrated for the Knoevenagel and nitroaldol condensation reactions, and the synthesis of coumarin derivatives. The catalytic activity of the microreactor was still intact even after 2 months.
Original languageEnglish
Pages (from-to)135-139
Number of pages5
JournalJournal of flow chemistry
Issue number3
Publication statusPublished - 2014


  • Knoevenagel condensation
  • Nitroaldol condensation
  • Piperazine catalysis
  • Microreactor
  • Coumarin synthesis
  • Polymer brushes


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