TY - JOUR
T1 - Platelet-Rich Blood Derivatives for Stem Cell-Based Tissue Engineering and Regeneration
AU - Masoudi, E.A.
AU - Ribas, J.
AU - Kaushik, G.
AU - Leijten, Jeroen Christianus Hermanus
AU - Khademhosseini, A.
PY - 2016/2/13
Y1 - 2016/2/13
N2 - Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails of autologous growth factors, which could provide an alternative for recombinant protein-based approaches. Platelet-rich blood derivatives, such as platelet-rich plasma, have consistently shown to potentiate stem cell proliferation, migration, and differentiation. Here, we review the spectrum of platelet-rich blood derivatives, discuss their current applications in tissue engineering and regenerative medicine, reflect on their effect on stem cells, and highlight current translational challenges.
AB - Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails of autologous growth factors, which could provide an alternative for recombinant protein-based approaches. Platelet-rich blood derivatives, such as platelet-rich plasma, have consistently shown to potentiate stem cell proliferation, migration, and differentiation. Here, we review the spectrum of platelet-rich blood derivatives, discuss their current applications in tissue engineering and regenerative medicine, reflect on their effect on stem cells, and highlight current translational challenges.
KW - METIS-316242
KW - IR-100017
KW - 22/4 OA procedure
U2 - 10.1007/s40778-016-0034-8
DO - 10.1007/s40778-016-0034-8
M3 - Article
SN - 2198-7866
VL - 2
SP - 33
EP - 42
JO - Current stem cell reports
JF - Current stem cell reports
IS - 1
ER -
