Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails of autologous growth factors, which could provide an alternative for recombinant protein-based approaches. Platelet-rich blood derivatives, such as platelet-rich plasma, have consistently shown to potentiate stem cell proliferation, migration, and differentiation. Here, we review the spectrum of platelet-rich blood derivatives, discuss their current applications in tissue engineering and regenerative medicine, reflect on their effect on stem cells, and highlight current translational challenges.
Masoudi, E. A., Ribas, J., Kaushik, G., Leijten, J. C. H., & Khademhosseini, A. (2016). Platelet-Rich Blood Derivatives for Stem Cell-Based Tissue Engineering and Regeneration. Current stem cell reports, 2(1), 33-42. https://doi.org/10.1007/s40778-016-0034-8