Platelet-Rich Blood Derivatives for Stem Cell-Based Tissue Engineering and Regeneration

E.A. Masoudi, J. Ribas, G. Kaushik, Jeroen Christianus Hermanus Leijten, A. Khademhosseini

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Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails of autologous growth factors, which could provide an alternative for recombinant protein-based approaches. Platelet-rich blood derivatives, such as platelet-rich plasma, have consistently shown to potentiate stem cell proliferation, migration, and differentiation. Here, we review the spectrum of platelet-rich blood derivatives, discuss their current applications in tissue engineering and regenerative medicine, reflect on their effect on stem cells, and highlight current translational challenges.
Original languageEnglish
Pages (from-to)33-42
Number of pages10
JournalCurrent stem cell reports
Issue number1
Publication statusPublished - 13 Feb 2016


  • METIS-316242
  • IR-100017
  • 22/4 OA procedure

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