Point-of-care lithium monitoring in whole blood using a disposable, prefilled and ready-to-use capillary electrophoresis microchip

D. Kohlheyer, Jan C.T. Eijkel, Stefan Lenk, S.O. Lenk, J. Floris, S.S. Staal, Steven Staal, Albert van den Berg

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    2 Citations (Scopus)

    Abstract

    This paper describes a microfluidic capillary electrophoresis device with integrated conductivity detection. The device satisfies all major requirements for pointof- care testing, i.e., simple handling, low sample volume, fast measurements, clear readout, and inexpensive disposable cartridge usage. The system is currently being utilized and commercialized for monitoring lithium in whole blood, however, can potentially be applied to various other ions present in blood, urine or other bodily fluids. The chip contains a single inlet only and will be shipped prefilled with background electrolyte, sealed and blistered; ready for use at the patient’s place. A single droplet of blood is required to be placed inside the cartridge to perform the analysis typically within a couple of minutes.
    Original languageUndefined
    Title of host publicationMicro Total Analysis Systems 2009
    EditorsT.S. Kim, Y-S Lee, T-D Chung, N.L. Jeon, S.H. Lee, K-Y Suh, J. Choo, Y-K Kim
    Place of PublicationSan Diego
    PublisherChemical and Biological Society
    Pages1731-1733
    Number of pages3
    ISBN (Print)978-0-9798064-2-1
    Publication statusPublished - 1 Nov 2009
    Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2009 - Jeju, Korea, Republic of
    Duration: 1 Nov 20095 Nov 2009
    Conference number: 13

    Publication series

    NamemicroTAS 2009
    PublisherChemical and Biological Society
    Volume2

    Conference

    Conference13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2009
    Abbreviated titleMicroTAS
    CountryKorea, Republic of
    CityJeju
    Period1/11/095/11/09

    Keywords

    • METIS-268931
    • EWI-17155
    • IR-69428

    Cite this

    Kohlheyer, D., Eijkel, J. C. T., Lenk, S., Lenk, S. O., Floris, J., Staal, S. S., ... van den Berg, A. (2009). Point-of-care lithium monitoring in whole blood using a disposable, prefilled and ready-to-use capillary electrophoresis microchip. In T. S. Kim, Y-S. Lee, T-D. Chung, N. L. Jeon, S. H. Lee, K-Y. Suh, J. Choo, ... Y-K. Kim (Eds.), Micro Total Analysis Systems 2009 (pp. 1731-1733). (microTAS 2009; Vol. 2). San Diego: Chemical and Biological Society.