Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle

S.V.N. de Vos; W.E. Hennink; Jan Feijen; J. Feijen; S.A. Koopmans; Dirk W. Grijpma; A.P. Sam; J.M.M. Hooymans

doi:10.1016/j.jconrel.2008.09.035

Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle

S.V.N. de Vos, W.E. Hennink (Editor), Jan Feijen, J. Feijen (Editor), S.A. Koopmans, Dirk W. Grijpma, A.P. Sam (Editor), J.M.M. Hooymans

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Abstract

Currently non-resorbable scleral buckles are used to repair a retinal detachment in the eye. In contrast to a non-resorbable implant, a resorbable implant will disappear after it has fulfilled its function. PTMC scleral buckles were implanted in six rabbits and explanted 10 weeks later. Histological analysis showed a mild tissue response, the degradation rate was up to 9.2 μm/day. Based on these results, it is expected that PTMC is a suitable material for scleral buckle application.

Original language	Undefined
Pages	e51-e52
DOIs	https://doi.org/10.1016/j.jconrel.2008.09.035
Publication status	Published - 2 Apr 2008
Event	10th European Symposium on Controlled Drug Delivery, ESCDD 2008 - Noordwijk aan Zee, Netherlands Duration: 2 Apr 2008 → 4 Apr 2008 Conference number: 10

Conference

Conference	10th European Symposium on Controlled Drug Delivery, ESCDD 2008
Abbreviated title	ESCDD
Country/Territory	Netherlands
City	Noordwijk aan Zee
Period	2/04/08 → 4/04/08

Keywords

IR-69412
METIS-254010

Access to Document

10.1016/j.jconrel.2008.09.035

Cite this

de Vos, S. V. N., Hennink, W. E. (Ed.), Feijen, J., Feijen, J. (Ed.), Koopmans, S. A., Grijpma, D. W., Sam, A. P. (Ed.), & Hooymans, J. M. M. (2008). Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle. e51-e52. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2008.09.035

@conference{f14c7b8396814b848e1439e49d983595,

title = "Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle",

abstract = "Currently non-resorbable scleral buckles are used to repair a retinal detachment in the eye. In contrast to a non-resorbable implant, a resorbable implant will disappear after it has fulfilled its function. PTMC scleral buckles were implanted in six rabbits and explanted 10 weeks later. Histological analysis showed a mild tissue response, the degradation rate was up to 9.2 μm/day. Based on these results, it is expected that PTMC is a suitable material for scleral buckle application.",

keywords = "IR-69412, METIS-254010",

author = "{de Vos}, S.V.N. and W.E. Hennink and Jan Feijen and J. Feijen and S.A. Koopmans and Grijpma, {Dirk W.} and A.P. Sam and J.M.M. Hooymans",

note = "Proceedings of the Tenth European Symposium on Controlled Drug Delivery ; 10th European Symposium on Controlled Drug Delivery, ESCDD 2008 ; Conference date: 02-04-2008 Through 04-04-2008",

year = "2008",

month = apr,

day = "2",

doi = "10.1016/j.jconrel.2008.09.035",

language = "Undefined",

pages = "e51--e52",

}

de Vos, SVN, Hennink, WE (ed.), Feijen, J, Feijen, J (ed.), Koopmans, SA, Grijpma, DW, Sam, AP (ed.) & Hooymans, JMM 2008, 'Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle', Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands, 2/04/08 - 4/04/08 pp. e51-e52. https://doi.org/10.1016/j.jconrel.2008.09.035

TY - CONF

T1 - Poly(1,3-trimethylene carbonate) networks as a resorbable scleral buckle

AU - de Vos, S.V.N.

AU - Feijen, Jan

AU - Koopmans, S.A.

AU - Grijpma, Dirk W.

AU - Hooymans, J.M.M.

A2 - Hennink, W.E.

A2 - Feijen, J.

A2 - Sam, A.P.

N1 - Conference code: 10

PY - 2008/4/2

Y1 - 2008/4/2

N2 - Currently non-resorbable scleral buckles are used to repair a retinal detachment in the eye. In contrast to a non-resorbable implant, a resorbable implant will disappear after it has fulfilled its function. PTMC scleral buckles were implanted in six rabbits and explanted 10 weeks later. Histological analysis showed a mild tissue response, the degradation rate was up to 9.2 μm/day. Based on these results, it is expected that PTMC is a suitable material for scleral buckle application.

AB - Currently non-resorbable scleral buckles are used to repair a retinal detachment in the eye. In contrast to a non-resorbable implant, a resorbable implant will disappear after it has fulfilled its function. PTMC scleral buckles were implanted in six rabbits and explanted 10 weeks later. Histological analysis showed a mild tissue response, the degradation rate was up to 9.2 μm/day. Based on these results, it is expected that PTMC is a suitable material for scleral buckle application.

KW - IR-69412

KW - METIS-254010

U2 - 10.1016/j.jconrel.2008.09.035

DO - 10.1016/j.jconrel.2008.09.035

M3 - Paper

SP - e51-e52

T2 - 10th European Symposium on Controlled Drug Delivery, ESCDD 2008

Y2 - 2 April 2008 through 4 April 2008

ER -