Polyelectrolyte complex micelles as wrapping for enzymes

During this PhD-project the applicability of polyelectrolyte complex micelles as "wrapping" for enzymes has been explored. Several aspects of this interdisciplinary topic have been addressed. The approach was as follows: rst, the preparation protocol of the micelles was studied (chapter 2-4), followed by the stability of the micelles against disintegration by salt (chapter 5 and 6). In chapter 7 self consistent eld calculations were performed to obtain information about the free energy associated with the incorporation of enzymes in polyelectrolyte complex micelles. The information gathered in these seven chapters was very useful for the interpretation of the enzymatic activity of lipase incorporated in these micelles. The results of that study are reported in chapter 8. In this summary the main ndings are discussed per chapter.