Polyethers for biomedical applications: Polymerization of propylene oxide by organozinc/organotin catalysts

Jan Gert Bots, Leen van der Does, Adriaan Bantjes, Jaap Broersma

    Research output: Contribution to journalArticleAcademic

    10 Citations (Scopus)
    83 Downloads (Pure)

    Abstract

    The polymerization of propylene oxide to obtain a high-molecular-weight polymer with an atactic structure required for the application as artificial blood vessels was investigated using combinations of organozinc and organotin compounds as catalyst. The composition of the most active catalyst, resulting from the reaction of diphenyltin sulfide with bis(3-dimethyl-aminopropyl)zinc, was found to be R(C6H5)2Sn(SZn)2R with R = (CH2)3N(CH3)2. Using this catalyst, an anionic coordination polymerization was observed with neither stereoselectivity nor living type or cationic features. At low catalyst concentration (0,03 mol-% Zn) a high-molecular-weight poly(propylene oxide) (PPOX) was obtained in 80-90% yield ([bar M ]w = 500000; 40% isotactic). Lowering of the catalyst concentration and increasing the polymerization temperature changed the kinetics and the stereochemistry of the polymerization leading to polymers of lower molecular weight and to a decrease in the isotactic PPOX fraction to 20%, probably due to an association of the catalytic species.
    Original languageEnglish
    Pages (from-to)1665-1681
    JournalMakromolekulare Chemie
    Volume188
    Issue number7
    DOIs
    Publication statusPublished - 1987

    Keywords

    • IR-70835

    Fingerprint Dive into the research topics of 'Polyethers for biomedical applications: Polymerization of propylene oxide by organozinc/organotin catalysts'. Together they form a unique fingerprint.

    Cite this