Polymers interfacing with biology

Frederik Wurm; Harm-Anton Klok

doi:10.2533/chimia.2011.659

Polymers interfacing with biology

Frederik Wurm
, Harm-Anton Klok^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

13 Downloads (Pure)

Abstract

The development of various controlled radical polymerization techniques as well as site- and residue specific strategies to modify peptides/proteins with synthetic polymers have made polymer chemistry a powerful tool to address materials problems at the biology interface. This article will present recent examples for bioactive surface modification and polymer therapeutics; it will highlight the use of controlled radical polymerization techniques and bioconjugation strategies to develop surface coatings for regenerative medicine and diagnostics, respectively, polymer-based nanomedicines.

Original language	English
Pages (from-to)	659-662
Number of pages	4
Journal	Chimia
Volume	65
Issue number	9
DOIs	https://doi.org/10.2533/chimia.2011.659
Publication status	Published - 1 Sept 2011
Externally published	Yes

Keywords

Biopolymers
PEGylation
Polymer brush
Polymer therapeutics
Surface modification

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AB - The development of various controlled radical polymerization techniques as well as site- and residue specific strategies to modify peptides/proteins with synthetic polymers have made polymer chemistry a powerful tool to address materials problems at the biology interface. This article will present recent examples for bioactive surface modification and polymer therapeutics; it will highlight the use of controlled radical polymerization techniques and bioconjugation strategies to develop surface coatings for regenerative medicine and diagnostics, respectively, polymer-based nanomedicines.

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KW - PEGylation

KW - Polymer brush

KW - Polymer therapeutics

KW - Surface modification

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Polymers interfacing with biology

Abstract

Keywords

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