Polypyrrole microtubules and their use in the construction of a third generation biosensor

C.G.J. Koopal*, M.C. Feiters, R.J.M. Nolte, B. de Ruiter, R.B.M. Schasfoort, R. Czajka, H. van Kempen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)
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Conducting polypyrrole microtubules have been prepared by template synthesis inside track-etch membranes. The interiors of these microtubules can adsorb the redox enzyme, glucose oxidase. The enzyme-coated tubules have been employed in the construction of a third generation amperometric biosensor for the determination of glucose. With this biosensor, glucose concentrations in the range 0.1-250 mM can be measured easily. The polypyrrole microtubules have been characterized by different microscopic techniques, including scanning tunnelling microscopy. Based on the microscopy data, a model is presented for the interaction between the conducting polymer and the glucose oxidase molecules.

Original languageEnglish
Pages (from-to)397-405
Number of pages9
JournalSynthetic metals
Issue number1-3
Publication statusPublished - 1 Sep 1992
Externally publishedYes


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