Polypyrrole microtubules and their use in the construction of a third generation biosensor

C.G.J. Koopal; M.C. Feiters; R.J.M. Nolte; B. de Ruiter; R.B.M. Schasfoort; R. Czajka; H. van Kempen

doi:10.1016/0379-6779(92)90295-T

Polypyrrole microtubules and their use in the construction of a third generation biosensor

C.G.J. Koopal^*, M.C. Feiters, R.J.M. Nolte, B. de Ruiter, R.B.M. Schasfoort, R. Czajka, H. van Kempen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Conducting polypyrrole microtubules have been prepared by template synthesis inside track-etch membranes. The interiors of these microtubules can adsorb the redox enzyme, glucose oxidase. The enzyme-coated tubules have been employed in the construction of a third generation amperometric biosensor for the determination of glucose. With this biosensor, glucose concentrations in the range 0.1-250 mM can be measured easily. The polypyrrole microtubules have been characterized by different microscopic techniques, including scanning tunnelling microscopy. Based on the microscopy data, a model is presented for the interaction between the conducting polymer and the glucose oxidase molecules.

Original language	English
Pages (from-to)	397-405
Number of pages	9
Journal	Synthetic metals
Volume	51
Issue number	1-3
DOIs	https://doi.org/10.1016/0379-6779(92)90295-T
Publication status	Published - 1 Sept 1992
Externally published	Yes

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title = "Polypyrrole microtubules and their use in the construction of a third generation biosensor",

abstract = "Conducting polypyrrole microtubules have been prepared by template synthesis inside track-etch membranes. The interiors of these microtubules can adsorb the redox enzyme, glucose oxidase. The enzyme-coated tubules have been employed in the construction of a third generation amperometric biosensor for the determination of glucose. With this biosensor, glucose concentrations in the range 0.1-250 mM can be measured easily. The polypyrrole microtubules have been characterized by different microscopic techniques, including scanning tunnelling microscopy. Based on the microscopy data, a model is presented for the interaction between the conducting polymer and the glucose oxidase molecules.",

author = "C.G.J. Koopal and M.C. Feiters and R.J.M. Nolte and {de Ruiter}, B. and R.B.M. Schasfoort and R. Czajka and {van Kempen}, H.",

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doi = "10.1016/0379-6779(92)90295-T",

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T1 - Polypyrrole microtubules and their use in the construction of a third generation biosensor

AU - Koopal, C.G.J.

AU - Feiters, M.C.

AU - Nolte, R.J.M.

AU - de Ruiter, B.

AU - Schasfoort, R.B.M.

AU - Czajka, R.

AU - van Kempen, H.

PY - 1992/9/1

Y1 - 1992/9/1

N2 - Conducting polypyrrole microtubules have been prepared by template synthesis inside track-etch membranes. The interiors of these microtubules can adsorb the redox enzyme, glucose oxidase. The enzyme-coated tubules have been employed in the construction of a third generation amperometric biosensor for the determination of glucose. With this biosensor, glucose concentrations in the range 0.1-250 mM can be measured easily. The polypyrrole microtubules have been characterized by different microscopic techniques, including scanning tunnelling microscopy. Based on the microscopy data, a model is presented for the interaction between the conducting polymer and the glucose oxidase molecules.

AB - Conducting polypyrrole microtubules have been prepared by template synthesis inside track-etch membranes. The interiors of these microtubules can adsorb the redox enzyme, glucose oxidase. The enzyme-coated tubules have been employed in the construction of a third generation amperometric biosensor for the determination of glucose. With this biosensor, glucose concentrations in the range 0.1-250 mM can be measured easily. The polypyrrole microtubules have been characterized by different microscopic techniques, including scanning tunnelling microscopy. Based on the microscopy data, a model is presented for the interaction between the conducting polymer and the glucose oxidase molecules.

U2 - 10.1016/0379-6779(92)90295-T

DO - 10.1016/0379-6779(92)90295-T

M3 - Article

AN - SCOPUS:0026916605

SN - 0379-6779

VL - 51

SP - 397

EP - 405

JO - Synthetic metals

JF - Synthetic metals

IS - 1-3

ER -

Polypyrrole microtubules and their use in the construction of a third generation biosensor

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