Possible roles of neural gap junctions in Parkinson's disease pathology

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

    28 Downloads (Pure)

    Abstract

    The pathology of Parkinson's disease (PD) is characterized by modified behavior of neuronal networks in the basal ganglia after depletion of dopamine. PD states show bursting neural activity and high synchronization among neurons as well as altered oscillations in local field potentials. These network modifications are thought to be directly related to PD motor symptoms such as tremor, akinesia and bradykinesia. Computational models of ...
    Original languageUndefined
    Title of host publicationProceedings 4th Dutch Bio-Medical Engineering conference 2013
    PublisherBME
    Pages8-9
    Number of pages2
    ISBN (Print)not assigned
    Publication statusPublished - 24 Jan 2013
    Event4th Dutch Bio-Medical Engineering Conference, BME 2013 - Hotel Zuiderduin, Egmond aan Zee, Netherlands
    Duration: 24 Jan 201325 Jan 2013
    Conference number: 4
    http://www.bme2013.nl/

    Publication series

    NameProceedings Dutch Bio-Medical Engineering conferences
    PublisherBME

    Conference

    Conference4th Dutch Bio-Medical Engineering Conference, BME 2013
    Abbreviated titleBME
    CountryNetherlands
    CityEgmond aan Zee
    Period24/01/1325/01/13
    OtherFourth Dutch BME Conference
    Internet address

    Keywords

    • EWI-23105
    • BSS-Neurotechnology and cellular engineering
    • Parkinson's Disease
    • METIS-296317
    • Dopamine
    • Gap junctions
    • IR-89412

    Cite this

    Schwab, B. C., van Wezel, R. J. A., Heida, T., & van Gils, S. A. (2013). Possible roles of neural gap junctions in Parkinson's disease pathology. In Proceedings 4th Dutch Bio-Medical Engineering conference 2013 (pp. 8-9). (Proceedings Dutch Bio-Medical Engineering conferences). BME.