Prediction of motion artifacts caused by translation in handheld laser speckle contrast imaging

Ata Chizari*, Wilson Tsong, Tom Knop, Wiendelt Steenbergen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
46 Downloads (Pure)


Significance: In handheld laser speckle contrast imaging (LSCI), motion artifacts (MA) are inevitable. Suppression of MA leads to a valid and objective assessment of tissue perfusion in a wide range of medical applications including dermatology and burns. Our study shines light on the sources of these artifacts, which have not yet been explored.We propose a model based on optical Doppler effect to predict speckle contrast drop as an indication of MA. Aim: We aim to theoretically model MA when an LSCI system measuring on static scattering media is subject to translational displacements.We validate the model using both simulation and experiments. This is the crucial first step toward creating robustness against MA. Approach: Our model calculates optical Doppler shifts in order to predict intensity correlation function and contrast of the time-integrated intensity as functions of applied speed based on illumination and detection wavevectors. To validate the theoretical predictions, computer simulation of the dynamic speckles has been carried out. Then experiments are performed by both high-speed and low-framerate imaging. The employed samples for the experiments are a highly scattering matte surface and a Delrin plate of finite scattering level in which volume scattering occurs. Results: An agreement has been found between theoretical prediction, simulation, and experimental results of both intensity correlation functions and speckle contrast. Coefficients in the proposed model have been linked to the physical parameters according to the experimental setups. Conclusions: The proposed model provides a quantitative description of the influence of the types of illumination and media in the creation of MA. The accurate prediction of MA caused by translation based on Doppler shifts makes our model suitable to study the influence of rotation. Also the model can be extended for the case of dynamic media, such as live tissue.

Original languageEnglish
Article number046005
JournalJournal of biomedical optics
Issue number4
Publication statusPublished - 1 Apr 2023


  • analytical models
  • biomedical optical imaging
  • computer simulation
  • Doppler effect
  • laser speckle contrast imaging
  • model-driven development
  • motion artifacts
  • numerical analysis
  • UT-Hybrid-D


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