Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic

Huipin Yuan, K. de Groot, Clemens van Blitterswijk, Joost Dick de Bruijn

Research output: Contribution to journalArticleAcademic

3 Citations (Scopus)
14 Downloads (Pure)

Abstract

Over the past decade we have demonstrated numerous times that calcium phosphates can be rendered with osteoinductive properties by introducing specific surface microstructures1. Since most of these calcium phosphates contained hydroxyapatite, they are either slowly or not resorbable2. Resorbability is an often sought after characteristic of calcium phosphates so that they can be gradually replaced by newly formed bone. The objective of this study was to prepare a resorbable surface microstructured tricalcium phosphate (TCP) ceramic and evaluate its osteoinductive property and resorption rate after intramuscular implantation in dogs. This material was then compared to the established and slowly resorbable osteoinductive biphasic calcium phosphate ceramic (BCP).
Original languageUndefined
Pages (from-to)14
JournalEuropean cells & materials
Volume16
Issue numberSuppl. 2
Publication statusPublished - 2008

Keywords

  • IR-80645

Cite this

Yuan, H., de Groot, K., van Blitterswijk, C., & de Bruijn, J. D. (2008). Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic. European cells & materials, 16(Suppl. 2), 14.
Yuan, Huipin ; de Groot, K. ; van Blitterswijk, Clemens ; de Bruijn, Joost Dick. / Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic. In: European cells & materials. 2008 ; Vol. 16, No. Suppl. 2. pp. 14.
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abstract = "Over the past decade we have demonstrated numerous times that calcium phosphates can be rendered with osteoinductive properties by introducing specific surface microstructures1. Since most of these calcium phosphates contained hydroxyapatite, they are either slowly or not resorbable2. Resorbability is an often sought after characteristic of calcium phosphates so that they can be gradually replaced by newly formed bone. The objective of this study was to prepare a resorbable surface microstructured tricalcium phosphate (TCP) ceramic and evaluate its osteoinductive property and resorption rate after intramuscular implantation in dogs. This material was then compared to the established and slowly resorbable osteoinductive biphasic calcium phosphate ceramic (BCP).",
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Yuan, H, de Groot, K, van Blitterswijk, C & de Bruijn, JD 2008, 'Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic', European cells & materials, vol. 16, no. Suppl. 2, pp. 14.

Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic. / Yuan, Huipin; de Groot, K.; van Blitterswijk, Clemens; de Bruijn, Joost Dick.

In: European cells & materials, Vol. 16, No. Suppl. 2, 2008, p. 14.

Research output: Contribution to journalArticleAcademic

TY - JOUR

T1 - Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic

AU - Yuan, Huipin

AU - de Groot, K.

AU - van Blitterswijk, Clemens

AU - de Bruijn, Joost Dick

N1 - eCM IX MUSCULOSKELETAL TRAUMA:50 YEARS OF AO RESEARCH June 15-18, 2008 - Convention Centre, Davos, Switzerland

PY - 2008

Y1 - 2008

N2 - Over the past decade we have demonstrated numerous times that calcium phosphates can be rendered with osteoinductive properties by introducing specific surface microstructures1. Since most of these calcium phosphates contained hydroxyapatite, they are either slowly or not resorbable2. Resorbability is an often sought after characteristic of calcium phosphates so that they can be gradually replaced by newly formed bone. The objective of this study was to prepare a resorbable surface microstructured tricalcium phosphate (TCP) ceramic and evaluate its osteoinductive property and resorption rate after intramuscular implantation in dogs. This material was then compared to the established and slowly resorbable osteoinductive biphasic calcium phosphate ceramic (BCP).

AB - Over the past decade we have demonstrated numerous times that calcium phosphates can be rendered with osteoinductive properties by introducing specific surface microstructures1. Since most of these calcium phosphates contained hydroxyapatite, they are either slowly or not resorbable2. Resorbability is an often sought after characteristic of calcium phosphates so that they can be gradually replaced by newly formed bone. The objective of this study was to prepare a resorbable surface microstructured tricalcium phosphate (TCP) ceramic and evaluate its osteoinductive property and resorption rate after intramuscular implantation in dogs. This material was then compared to the established and slowly resorbable osteoinductive biphasic calcium phosphate ceramic (BCP).

KW - IR-80645

M3 - Article

VL - 16

SP - 14

JO - European cells & materials

JF - European cells & materials

SN - 1473-2262

IS - Suppl. 2

ER -

Yuan H, de Groot K, van Blitterswijk C, de Bruijn JD. Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic. European cells & materials. 2008;16(Suppl. 2):14.