Preparation of cellulose-based sponges for wound dressing and healing

J. Kazlauske, Victoria Dutschk, J. Liesiene

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

    127 Downloads (Pure)

    Abstract

    For healing of chronic or burn wounds, polymeric sponges have been recently applied. Due to a high absorption capacity, noncitotoxicity and good swelling capabilities, for their production natural polymers are often used. In this study, macroporous regenerated cellulose was evaluated as a matrix for wound dressing materials. Active compounds, such as antibiotic neomycin and phenolic compound quercetin were immobilized in the cellulosic matrix aimed to promote wound healing process. Active compounds in the sponges were immobilized alone or with water-soluble hydroxyethylcellulose or carboxymethylcellulose. It was found that the way of preparation of sponges can affect their porosity, moisture absorption and drying rate. The best sponges for wound dressing materials were formed from freeze-dried macroporous regenerated cellulose in which was later immobilised hydroxyethylcellulose or carboxymethylcellulos with active compounds.
    Original languageEnglish
    Title of host publicationProceedings of the 13th AUTEX World Textile Conference 2013
    EditorsA. Dörfel, M. Vignaesh Sankaran
    Place of PublicationGermany
    PublisherITM, TU Dresden
    Pages1-2
    ISBN (Print)978-3-86780-343-4
    Publication statusPublished - 22 May 2013
    Event13th AUTEX World Textile Conference 2013 - Dresden, Germany
    Duration: 22 May 201324 May 2013
    Conference number: 13

    Publication series

    Name367
    PublisherITM, TU Dresden

    Conference

    Conference13th AUTEX World Textile Conference 2013
    CountryGermany
    CityDresden
    Period22/05/1324/05/13

    Keywords

    • IR-89052
    • METIS-301933

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