Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2

S.P. Nalawade, W.E. Hennink (Editor), D. Westerman, J. Feijen (Editor), A.P. Sam (Editor), G. Leeke, R.C.D. Santos, Dirk W. Grijpma, Jan Feijen

Research output: Contribution to conferencePaperAcademic

Abstract

Porous poly(trimethylene carbonate) structures can readily be prepared using high pressure CO2. Differences in CO2 solubility in the polymer matrix at the different processing temperatures and pressures lead to different pore morphologies upon depressurization. Furthermore, crystallization of the initially amorphous polymer leads to stable porous structures. This variation in pore structure can be used to tailor polymer matrix degradation rates and drug release profiles
Original languageUndefined
Pagese73-e75
DOIs
Publication statusPublished - 2 Apr 2008
Event10th European Symposium on Controlled Drug Delivery, ESCDD 2008 - Noordwijk aan Zee, Netherlands
Duration: 2 Apr 20084 Apr 2008
Conference number: 10

Conference

Conference10th European Symposium on Controlled Drug Delivery, ESCDD 2008
Abbreviated titleESCDD
CountryNetherlands
CityNoordwijk aan Zee
Period2/04/084/04/08

Keywords

  • EC Grant Agreement nr.: FP6/500465
  • IR-69318
  • METIS-254003

Cite this

Nalawade, S. P., Hennink, W. E. (Ed.), Westerman, D., Feijen, J. (Ed.), Sam, A. P. (Ed.), Leeke, G., ... Feijen, J. (2008). Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2. e73-e75. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2008.09.067
Nalawade, S.P. ; Hennink, W.E. (Editor) ; Westerman, D. ; Feijen, J. (Editor) ; Sam, A.P. (Editor) ; Leeke, G. ; Santos, R.C.D. ; Grijpma, Dirk W. ; Feijen, Jan. / Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands.
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abstract = "Porous poly(trimethylene carbonate) structures can readily be prepared using high pressure CO2. Differences in CO2 solubility in the polymer matrix at the different processing temperatures and pressures lead to different pore morphologies upon depressurization. Furthermore, crystallization of the initially amorphous polymer leads to stable porous structures. This variation in pore structure can be used to tailor polymer matrix degradation rates and drug release profiles",
keywords = "EC Grant Agreement nr.: FP6/500465, IR-69318, METIS-254003",
author = "S.P. Nalawade and W.E. Hennink and D. Westerman and J. Feijen and A.P. Sam and G. Leeke and R.C.D. Santos and Grijpma, {Dirk W.} and Jan Feijen",
note = "Proceedings of the Tenth European Symposium on Controlled Drug Delivery ; null ; Conference date: 02-04-2008 Through 04-04-2008",
year = "2008",
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Nalawade, SP, Hennink, WE (ed.), Westerman, D, Feijen, J (ed.), Sam, AP (ed.), Leeke, G, Santos, RCD, Grijpma, DW & Feijen, J 2008, 'Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2' Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands, 2/04/08 - 4/04/08, pp. e73-e75. https://doi.org/10.1016/j.jconrel.2008.09.067

Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2. / Nalawade, S.P.; Hennink, W.E. (Editor); Westerman, D.; Feijen, J. (Editor); Sam, A.P. (Editor); Leeke, G.; Santos, R.C.D.; Grijpma, Dirk W.; Feijen, Jan.

2008. e73-e75 Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands.

Research output: Contribution to conferencePaperAcademic

TY - CONF

T1 - Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2

AU - Nalawade, S.P.

AU - Westerman, D.

AU - Leeke, G.

AU - Santos, R.C.D.

AU - Grijpma, Dirk W.

AU - Feijen, Jan

A2 - Hennink, W.E.

A2 - Feijen, J.

A2 - Sam, A.P.

N1 - Proceedings of the Tenth European Symposium on Controlled Drug Delivery

PY - 2008/4/2

Y1 - 2008/4/2

N2 - Porous poly(trimethylene carbonate) structures can readily be prepared using high pressure CO2. Differences in CO2 solubility in the polymer matrix at the different processing temperatures and pressures lead to different pore morphologies upon depressurization. Furthermore, crystallization of the initially amorphous polymer leads to stable porous structures. This variation in pore structure can be used to tailor polymer matrix degradation rates and drug release profiles

AB - Porous poly(trimethylene carbonate) structures can readily be prepared using high pressure CO2. Differences in CO2 solubility in the polymer matrix at the different processing temperatures and pressures lead to different pore morphologies upon depressurization. Furthermore, crystallization of the initially amorphous polymer leads to stable porous structures. This variation in pore structure can be used to tailor polymer matrix degradation rates and drug release profiles

KW - EC Grant Agreement nr.: FP6/500465

KW - IR-69318

KW - METIS-254003

U2 - 10.1016/j.jconrel.2008.09.067

DO - 10.1016/j.jconrel.2008.09.067

M3 - Paper

SP - e73-e75

ER -

Nalawade SP, Hennink WE, (ed.), Westerman D, Feijen J, (ed.), Sam AP, (ed.), Leeke G et al. Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2. 2008. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2008.09.067