Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2

S.P. Nalawade, W.E. Hennink (Editor), D. Westerman, J. Feijen (Editor), A.P. Sam (Editor), G. Leeke, R.C.D. Santos, Dirk W. Grijpma, Jan Feijen

Research output: Contribution to conferencePaper

Abstract

Porous poly(trimethylene carbonate) structures can readily be prepared using high pressure CO2. Differences in CO2 solubility in the polymer matrix at the different processing temperatures and pressures lead to different pore morphologies upon depressurization. Furthermore, crystallization of the initially amorphous polymer leads to stable porous structures. This variation in pore structure can be used to tailor polymer matrix degradation rates and drug release profiles
Original languageUndefined
Pagese73-e75
DOIs
Publication statusPublished - 2 Apr 2008
Event10th European Symposium on Controlled Drug Delivery, ESCDD 2008 - Noordwijk aan Zee, Netherlands
Duration: 2 Apr 20084 Apr 2008
Conference number: 10

Conference

Conference10th European Symposium on Controlled Drug Delivery, ESCDD 2008
Abbreviated titleESCDD
CountryNetherlands
CityNoordwijk aan Zee
Period2/04/084/04/08

Keywords

  • EC Grant Agreement nr.: FP6/500465
  • IR-69318
  • METIS-254003

Cite this

Nalawade, S. P., Hennink, W. E. (Ed.), Westerman, D., Feijen, J. (Ed.), Sam, A. P. (Ed.), Leeke, G., ... Feijen, J. (2008). Preparation of porous poly(trimethylene carbonate structures for controlled release applications using high pressure CO2. e73-e75. Paper presented at 10th European Symposium on Controlled Drug Delivery, ESCDD 2008, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2008.09.067