Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers

W.E. Hennink (Editor), C. Hiemstra, Zhiyuan Zhong, J. Feijen (Editor), T Sam (Editor), S.R. van Tomme, Pieter J. Dijkstra, Jan Feijen

Research output: Contribution to conferencePaperAcademic

8 Citations (Scopus)

Abstract

The release of two model proteins, lysozyme and immunoglobulin G (IgG) from injectable, fast gelling, biodegradable hydrogels composed of PEG–PLLA and PEG–PDLA star block copolymers was investigated. Lysozyme was quantitatively released in 10 days. The release of IgG was slower and after 20 days 40–60% was released depending on the composition of the gel.
Original languageUndefined
Pages19-21
DOIs
Publication statusPublished - 5 Apr 2006
Event9th European Symposium on Controlled Drug Delivery, ESCDD 2006 - Noordwijk aan Zee, Netherlands
Duration: 5 Apr 20067 Apr 2006
Conference number: 9

Conference

Conference9th European Symposium on Controlled Drug Delivery, ESCDD 2006
Abbreviated titleESCDD
CountryNetherlands
CityNoordwijk aan Zee
Period5/04/067/04/06

Keywords

  • METIS-236892
  • IR-71107

Cite this

Hennink, W. E. (Ed.), Hiemstra, C., Zhong, Z., Feijen, J. (Ed.), Sam, T. (Ed.), van Tomme, S. R., ... Feijen, J. (2006). Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers. 19-21. Paper presented at 9th European Symposium on Controlled Drug Delivery, ESCDD 2006, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2006.09.028
Hennink, W.E. (Editor) ; Hiemstra, C. ; Zhong, Zhiyuan ; Feijen, J. (Editor) ; Sam, T (Editor) ; van Tomme, S.R. ; Dijkstra, Pieter J. ; Feijen, Jan. / Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers. Paper presented at 9th European Symposium on Controlled Drug Delivery, ESCDD 2006, Noordwijk aan Zee, Netherlands.
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title = "Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers",
abstract = "The release of two model proteins, lysozyme and immunoglobulin G (IgG) from injectable, fast gelling, biodegradable hydrogels composed of PEG–PLLA and PEG–PDLA star block copolymers was investigated. Lysozyme was quantitatively released in 10 days. The release of IgG was slower and after 20 days 40–60{\%} was released depending on the composition of the gel.",
keywords = "METIS-236892, IR-71107",
author = "W.E. Hennink and C. Hiemstra and Zhiyuan Zhong and J. Feijen and T Sam and {van Tomme}, S.R. and Dijkstra, {Pieter J.} and Jan Feijen",
note = "Proceedings of the Ninth European Symposium on Controlled Drug Delivery ; null ; Conference date: 05-04-2006 Through 07-04-2006",
year = "2006",
month = "4",
day = "5",
doi = "10.1016/j.jconrel.2006.09.028",
language = "Undefined",
pages = "19--21",

}

Hennink, WE (ed.), Hiemstra, C, Zhong, Z, Feijen, J (ed.), Sam, T (ed.), van Tomme, SR, Dijkstra, PJ & Feijen, J 2006, 'Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers' Paper presented at 9th European Symposium on Controlled Drug Delivery, ESCDD 2006, Noordwijk aan Zee, Netherlands, 5/04/06 - 7/04/06, pp. 19-21. https://doi.org/10.1016/j.jconrel.2006.09.028

Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers. / Hennink, W.E. (Editor); Hiemstra, C.; Zhong, Zhiyuan; Feijen, J. (Editor); Sam, T (Editor); van Tomme, S.R.; Dijkstra, Pieter J.; Feijen, Jan.

2006. 19-21 Paper presented at 9th European Symposium on Controlled Drug Delivery, ESCDD 2006, Noordwijk aan Zee, Netherlands.

Research output: Contribution to conferencePaperAcademic

TY - CONF

T1 - Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers

AU - Hiemstra, C.

AU - Zhong, Zhiyuan

AU - van Tomme, S.R.

AU - Dijkstra, Pieter J.

AU - Feijen, Jan

A2 - Hennink, W.E.

A2 - Feijen, J.

A2 - Sam, T

N1 - Proceedings of the Ninth European Symposium on Controlled Drug Delivery

PY - 2006/4/5

Y1 - 2006/4/5

N2 - The release of two model proteins, lysozyme and immunoglobulin G (IgG) from injectable, fast gelling, biodegradable hydrogels composed of PEG–PLLA and PEG–PDLA star block copolymers was investigated. Lysozyme was quantitatively released in 10 days. The release of IgG was slower and after 20 days 40–60% was released depending on the composition of the gel.

AB - The release of two model proteins, lysozyme and immunoglobulin G (IgG) from injectable, fast gelling, biodegradable hydrogels composed of PEG–PLLA and PEG–PDLA star block copolymers was investigated. Lysozyme was quantitatively released in 10 days. The release of IgG was slower and after 20 days 40–60% was released depending on the composition of the gel.

KW - METIS-236892

KW - IR-71107

U2 - 10.1016/j.jconrel.2006.09.028

DO - 10.1016/j.jconrel.2006.09.028

M3 - Paper

SP - 19

EP - 21

ER -

Hennink WE, (ed.), Hiemstra C, Zhong Z, Feijen J, (ed.), Sam T, (ed.), van Tomme SR et al. Protein release from injectable stereocomplexed hydrogels based on PEG-PDLA and PEG-PLLA star block copolymers. 2006. Paper presented at 9th European Symposium on Controlled Drug Delivery, ESCDD 2006, Noordwijk aan Zee, Netherlands. https://doi.org/10.1016/j.jconrel.2006.09.028