TY - JOUR
T1 - Pulmonary congestion and mortality during venoarterial extracorporeal membrane oxygenation (VA-ECMO)
T2 - does time matter?
AU - van der Wal, Pieter S.
AU - Zwetsloot, Peter-Paul
AU - Cremer, Olaf L
AU - Donker, Dirk W.
AU - Meuwese, Christiaan L.
N1 - Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/4
Y1 - 2021/4
N2 - In a recent edition of this Journal, an intriguing study was published which examined the association between (development of) pulmonary congestion (PC) and mortality in patients with post-cardiotomy cardiogenic shock requiring extracorporeal membrane oxygenation (ECMO). [ [1] ] Distelmaier and colleagues observed in 266 patients that presence of PC on days 3 and 5 —but not day 0— after ECMO initiation was negatively associated with survival. We were struck by the apparent disparity in impact of PC on mortality between first and subsequent days. We are concerned that two methodological issues might have caused this apparent difference; selection (survivor) bias and confounding.
AB - In a recent edition of this Journal, an intriguing study was published which examined the association between (development of) pulmonary congestion (PC) and mortality in patients with post-cardiotomy cardiogenic shock requiring extracorporeal membrane oxygenation (ECMO). [ [1] ] Distelmaier and colleagues observed in 266 patients that presence of PC on days 3 and 5 —but not day 0— after ECMO initiation was negatively associated with survival. We were struck by the apparent disparity in impact of PC on mortality between first and subsequent days. We are concerned that two methodological issues might have caused this apparent difference; selection (survivor) bias and confounding.
KW - n/a OA procedure
U2 - 10.1016/j.ejim.2020.12.005
DO - 10.1016/j.ejim.2020.12.005
M3 - Comment/Letter to the editor
C2 - 33353802
SN - 0953-6205
VL - 86
SP - 107
EP - 107
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
ER -