A setup for pulsed-laser Doppler flowmetry ~LDF! measurements has been built and tested. Measurements were carried out comparing continuous-wave and pulsed LDF. With pulsed LDF a higher peak power can be injected into the tissue without exceeding the safety limits. This enables a much larger spacing between the locations of illumination and detection. Thus, the penetration depth, and thus the measurement volume, can be enlarged using the pulsed-LDF method. This method will allow, e.g., monitoring of the cerebral perfusion.
Kolkman, R. G. M., Hondebrink, E., Bolt, R. A., Steenbergen, W., & de Mul, F. F. M. (2001). Pulsed-laser Doppler flowmetry provides basis for deep perfusion probing. Review of scientific instruments, 72(11), 4242-4244. https://doi.org/10.1063/1.1409566