Raman imaging and lipidomic analysis of lipid droplets in (activated) hepatic stellate cells

A.B. Vaandrager, N. Testerink, M. Ajat, M. Houweling, J.F.H.M. Brouwers, V.V. Pully, H.J. van Manen, Cornelis Otto, J.B. Helms

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Abstract

In eukaryotic cells the excess of hydrophobic molecules is stored in special organelles named lipid droplets (LDs). These droplets contain triacylglycerides, cholesteryl esters and/or retinyl esters, depending on the function of the cell in which they reside. Retinyl esters, the storage form of vitamin A, are mainly stored in LDs in hepatic stellate cells (HSC), which comprise about 5–10% of total liver cells.
Original languageUndefined
Pages (from-to)S7-S8
JournalChemistry and physics of lipids
Volume160
Issue numberSuppl.
DOIs
Publication statusPublished - 2009

Keywords

  • IR-80143

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