TY - JOUR
T1 - Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve
AU - Koçer, A.
AU - Walko, M.
AU - Bulten, E.
AU - Halza, E.
AU - Feringa, B.L.
AU - Meijberg, W.
PY - 2006
Y1 - 2006
N2 - Open channels: Chemical modulators are developed to convert a naturally occurring channel protein into a pH-actuated nanovalve. The pH interval, sensitivity, and activation of the valve by channel opening are tunable through the design of the modulators. The valve is useful for releasing or mixing the contents of liposomes at a desired location, time, and dosage, for example, in micro/nanosensory and delivery devices (see picture).
AB - Open channels: Chemical modulators are developed to convert a naturally occurring channel protein into a pH-actuated nanovalve. The pH interval, sensitivity, and activation of the valve by channel opening are tunable through the design of the modulators. The valve is useful for releasing or mixing the contents of liposomes at a desired location, time, and dosage, for example, in micro/nanosensory and delivery devices (see picture).
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-33746216389&partnerID=MN8TOARS
U2 - 10.1002/anie.200503403
DO - 10.1002/anie.200503403
M3 - Article
SN - 1433-7851
VL - 45
SP - 3126
EP - 3130
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 19
ER -