Abstract
In this paper, we report the realization and characterization of a four-channel integrated optical Young interferometer (YI), which enables simultaneous and independent monitoring of three binding processes. The simultaneous and independent measurement of three different glucose concentrations shows the multi-purpose feature of such device. The phase resolution for different pairs of channels was /spl sim/1/spl times/10/sup -4/ fringes, which corresponds to a refractive index resolution of /spl sim/8.5/spl times/10/sup -8/ . The observed errors, which are caused due to mismatching of spatial frequencies of individual interference patterns with those determined from the CCD camera, have been reduced by using different reduction schemes. In addition, we have investigated a novel method for discrimination of the refractive index change from the thickness of a bound layer during an immunoreaction, as well as measuring the temperature change the takes place during such a process.
Original language | Undefined |
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Title of host publication | The 12th International Conference on Solid State Sensors, Actuators and Microsystems |
Place of Publication | Boston, USA |
Publisher | IEEE |
Pages | 1192-1196 |
Number of pages | 5 |
ISBN (Print) | 0-7803-7731-1 |
DOIs | |
Publication status | Published - 9 Jun 2003 |
Event | 12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Boston, United States Duration: 8 Jun 2003 → 12 Jun 2003 Conference number: 12 |
Publication series
Name | |
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Publisher | IEEE |
Number | 03TH8664 |
Volume | 2 |
Conference
Conference | 12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 |
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Abbreviated title | TRANSDUCERS 2003 |
Country/Territory | United States |
City | Boston |
Period | 8/06/03 → 12/06/03 |
Keywords
- IR-40631
- METIS-213026