Reconstruction of short time PET scans using Bregman iterations

Jahn Müller*, Christoph Brune, Alex Sawatzky, Thomas Kösters, Klaus P. Schäfers, Martin Burger

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

15 Citations (Scopus)

Abstract

We propose a method for reconstructing data from short time positron emission tomography (PET) scans, i.e data acquired over a short time period. In this case standard reconstruction methods deliver only unsatisfactory and noisy results. We incorporate a priori information directly in the reconstruction process via nonlinear variational methods. A promising approach was the so-called EMTV algorithm, where the negative log-likelihood functional, which is minimized in the expectation maximization (ML-EM) algorithm, was modified by adding a total variation (TV) term. To improve the results and to overcome the issue of the loss of contrast we extend the algorithm by an inverse scale space method using Bregman distances, to which we refer as BREGMAN EMTV algorithm. The methods are tested on short time (5 and 30 seconds) FDG measurements of the thorax. We can show that the EMTV approach can effectively reduce the noise, but still introduces an oversmoothing, which is eliminated by the BREGMAN EMTV method, obtaining a reconstruction of comparable quality to the corresponding long time (20 and 7 minutes) scan. This correction for the loss of contrast is necessary to obtain quantitative PET images.

Original languageEnglish
Title of host publication2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PublisherIEEE
Pages2383-2385
Number of pages3
ISBN (Print)9781467301183
DOIs
Publication statusPublished - 1 Jan 2011
Externally publishedYes
EventIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011 - Valencia, Spain
Duration: 23 Oct 201129 Oct 2011
http://www.nss-mic.org/2011/

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

ConferenceIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Abbreviated titleNSS/MIC
CountrySpain
CityValencia
Period23/10/1129/10/11
Internet address

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