TY - JOUR
T1 - Reduced contrast medium in abdominal aorta CTA using a multiphasic injection technique
AU - Nijhof, Wouter
AU - van der Vos, Charlotte S.
AU - Anninga, Bauke
AU - Stegehuis, Paulien L.
AU - Jager, Gerrit J.
AU - Rutten, Matthieu J.C.M.
PY - 2012/9/30
Y1 - 2012/9/30
N2 - Purpose: The purpose of this study was to determine if with a multiphasic injection technique the admin- istered amount of contrast medium for abdominal computerized tomographic angiography (CTA) can be decreased, whilst improving CT image quality. Materials and methods: In 30 patients a multiphasic injection method was compared to the standard uniphasic contrast medium injection protocol. Fifteen patients underwent abdominal CTA with a standard uniphasic injection protocol (protocol I) receiving 100 mL of a non-ionic radiopaque contrast agent (Iover- sol). The second group of 15 patients underwent CTA with a multiphasic injection protocol (protocol II) receiving a total of 89 mL Ioversol. Vascular contrast enhancement and difference in enhancement uni- formity were assessed quantitatively and image quality was assessed by three independent radiologists. Results: Quantitative assessment of the vascular contrast enhancement showed that there was no signif- icant difference in enhancement uniformity for patients between the protocols. The image quality was rated as being good to excellent in 81.8% and 88.0% of the scans, for protocol I and protocol II, respectively. However these differences were not statistically significant.
Conclusion: By using a multiphasic injection technique with CTA of the abdominal aorta a reduction of 11 percent of contrast medium can be realized. Enhancement patterns are quantitatively as well as qualitatively comparable to the standard contrast medium injection protocol.
AB - Purpose: The purpose of this study was to determine if with a multiphasic injection technique the admin- istered amount of contrast medium for abdominal computerized tomographic angiography (CTA) can be decreased, whilst improving CT image quality. Materials and methods: In 30 patients a multiphasic injection method was compared to the standard uniphasic contrast medium injection protocol. Fifteen patients underwent abdominal CTA with a standard uniphasic injection protocol (protocol I) receiving 100 mL of a non-ionic radiopaque contrast agent (Iover- sol). The second group of 15 patients underwent CTA with a multiphasic injection protocol (protocol II) receiving a total of 89 mL Ioversol. Vascular contrast enhancement and difference in enhancement uni- formity were assessed quantitatively and image quality was assessed by three independent radiologists. Results: Quantitative assessment of the vascular contrast enhancement showed that there was no signif- icant difference in enhancement uniformity for patients between the protocols. The image quality was rated as being good to excellent in 81.8% and 88.0% of the scans, for protocol I and protocol II, respectively. However these differences were not statistically significant.
Conclusion: By using a multiphasic injection technique with CTA of the abdominal aorta a reduction of 11 percent of contrast medium can be realized. Enhancement patterns are quantitatively as well as qualitatively comparable to the standard contrast medium injection protocol.
KW - Multiphasic injection
KW - Image quality
KW - EWI-24925
KW - Contrast sensitivity
KW - CT angiography
KW - IR-92855
U2 - 10.1016/j.ejrad.2012.09.022
DO - 10.1016/j.ejrad.2012.09.022
M3 - Article
VL - 82
SP - 252
EP - 257
JO - European journal of radiology
JF - European journal of radiology
SN - 0720-048X
IS - 2
ER -