Reduction of contrast medium volume in abdominal aorta CTA: Multiphasic injection technique versus a test bolus volume

Wouter Nijhof, Charlotte S. van der Vos, Bauke Anninga, Gerrit J. Jager, Matthieu J.C.M. Rutten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)


Objective: The purpose of this study is to reduce the administered contrast medium volume in abdominal CTA by using a test bolus injection, with the preservation of adequate quantitative and qualitative vessel enhancement.

Study design: For this technical efficacy study 30 patients, who were referred for a CTA examination of the abdominal aorta, were included. Randomly 15 patients were assigned to undergo a multiphasic injection protocol and received 89 mL of contrast medium (Optiray 350) (protocol I). Fifteen patients were assigned to the test bolus injection protocol (protocol II), which implies injection of a 10 mL test bolus of Optiray 350 prior to performing CTA with a 40 mL of contrast medium. Quantitative assessment of vascular enhancement was performed by measuring the amount of Hounsfield Units in the aorta at 30 positions from the celiac trunk to the iliac arteries in both groups. Qualitative assessment was performed by three radiologists who scored the images at a 5-point scale.

Results: Quantitative assessment showed that there was no significant difference in vascular enhance- ment for patients between the two protocols, with mean attenuation values of 280.9±50.84HU and 258.60 ± 39.28 HU, respectively. The image quality of protocol I was rated 4.31 (range: 3.67/5.00) and of protocol II 4.11 (range: 2.67/5.00). These differences were not statistically significant.

Conclusion: This study showed that by using a test bolus injection and the administration of 50 mL of con- trast medium overall, CTA of the abdominal aorta can reliably be performed, with regard to quantitative and qualitative adequate vessel enhancement.
Original languageEnglish
Pages (from-to)1373-1378
Number of pages6
JournalEuropean journal of radiology
Issue number9
Publication statusPublished - 31 Mar 2013


  • Abdominal aorta CT angiography Iodinated contrast medium Test bolus injection Image quality
  • Image quality
  • Test bolus injection
  • CT angiography
  • Abdominal aorta
  • Iodinated contrast medium
  • n/a OA procedure


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