Region-of-interest breast studies using the Twente Photoacoustic Mammoscope (PAM)

Srirang Manohar*, Sanne E. Vaartjes, Johan C.G. Van Hespen, Joost M. Klaase, Frank M. Van Den Engh, Andy K.H. Thé, Wiendelt Steenbergen, Ton G. Van Leeuwen

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    10 Citations (Scopus)
    19 Downloads (Pure)

    Abstract

    The Twente Photoacoustic Mammoscope (PAM) is based on generating laser-induced ultrasound from absorbing structures in the breast. The heart of the instrument is a flat PVDF based detector matrix comprising 590 active elements. The exciting source is an Nd:YAG laser operating at 1064 nm with 5 ns pulses. The instrument is built around a hospital bed. A study protocol was designed to explore the feasibility of using the photoacoustic technique as embodied in PAM to detect cancer in the breasts of patients with suspect/symptomatic breasts. The protocol was approved by a Medical Ethics testing committee and the instrument approved for laser and electrical safety. The protocol was executed at the Medisch Spectrum Twente by using the mammoscope to obtain photoacoustic region-of-interest (ROI) images of the suspect/symptomatic breasts. We report on one case and compare the photoacoustic images obtained with x-ray mammograms and ultrasound images.

    Original languageEnglish
    Title of host publicationPhotons Plus Ultrasound
    Subtitle of host publicationImaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
    Number of pages9
    Volume6437
    DOIs
    Publication statusPublished - 30 Apr 2007
    EventPhotons Plus Ultrasound: Imaging and Sensing 2007: 8th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - San Jose, United States
    Duration: 13 Feb 200715 Feb 2007

    Publication series

    NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume6437
    ISSN (Print)1605-7422

    Conference

    ConferencePhotons Plus Ultrasound: Imaging and Sensing 2007
    CountryUnited States
    CitySan Jose
    Period13/02/0715/02/07

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