Reliability of handheld laser speckle contrast perfusion imaging demonstrated in psoriasis lesions

Ata Chizari*, Mirjam J. Schaap, Tom Knop, Marieke M.B. Seyger, Wiendelt Steenbergen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Downloads (Pure)

Abstract

We assessed the reliability of handheld laser speckle contrast perfusion imaging by evaluating mounted/handheld measurement pairs operated on psoriasis lesions in three steps. First, we made a denoised perfusion map per measurement based on spatial alignment of raw speckle frames and temporal averaging of perfusion frames. Second, we used the measured on-surface speed information to compensate the movement-induced perfusion by extrapolation of the local perfusion values to the value corresponds to zero on-surface speed. Third, we compared mounted/handheld measurement pairs based on perfusion inhomogeneity and increased perilesional perfusion criteria independent of the movement artefact compensation mentioned in the second step. We conclude that after proper post-processing, handheld LSCI measurements can be as reliable as mounted measurements in terms of geometrical distorting, but with challenges to be overcome for correcting perfusion values.

Original languageEnglish
Title of host publicationPhotonics in Dermatology and Plastic Surgery 2022
EditorsBernard Choi, Haishan Zeng
PublisherSPIE Press
Volume11934
ISBN (Electronic)9781510647404
ISBN (Print)978-1-5106-4739-8
DOIs
Publication statusPublished - 3 Mar 2022
EventPhotonics in Dermatology and Plastic Surgery 2022 - San Francisco, United States
Duration: 22 Jan 202223 Jan 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11934
ISSN (Print)1605-7422

Conference

ConferencePhotonics in Dermatology and Plastic Surgery 2022
Country/TerritoryUnited States
CitySan Francisco
Period22/01/2223/01/22

Keywords

  • enhanced correlation coefficient maximization
  • handheld
  • image alignment
  • laser speckle contrast imaging
  • mean separation segmentation
  • movement artefacts
  • on-surface speeds
  • psoriasis
  • 22/2 OA procedure

Fingerprint

Dive into the research topics of 'Reliability of handheld laser speckle contrast perfusion imaging demonstrated in psoriasis lesions'. Together they form a unique fingerprint.

Cite this