@inproceedings{4321a1c2c652484f82da78993a825387,
title = "Reliability of handheld laser speckle contrast perfusion imaging demonstrated in psoriasis lesions",
abstract = "We assessed the reliability of handheld laser speckle contrast perfusion imaging by evaluating mounted/handheld measurement pairs operated on psoriasis lesions in three steps. First, we made a denoised perfusion map per measurement based on spatial alignment of raw speckle frames and temporal averaging of perfusion frames. Second, we used the measured on-surface speed information to compensate the movement-induced perfusion by extrapolation of the local perfusion values to the value corresponds to zero on-surface speed. Third, we compared mounted/handheld measurement pairs based on perfusion inhomogeneity and increased perilesional perfusion criteria independent of the movement artefact compensation mentioned in the second step. We conclude that after proper post-processing, handheld LSCI measurements can be as reliable as mounted measurements in terms of geometrical distorting, but with challenges to be overcome for correcting perfusion values.",
keywords = "enhanced correlation coefficient maximization, handheld, image alignment, laser speckle contrast imaging, mean separation segmentation, movement artefacts, on-surface speeds, psoriasis, 22/2 OA procedure",
author = "Ata Chizari and Schaap, {Mirjam J.} and Tom Knop and Seyger, {Marieke M.B.} and Wiendelt Steenbergen",
note = "Funding Information: This study was supported by the Open Technology program of the Netherlands Organization for Scientific Research (NWO), Domain Applied and Engineering Sciences, under grant number 14538. Publisher Copyright: {\textcopyright} 2022 SPIE; Photonics in Dermatology and Plastic Surgery 2022 ; Conference date: 22-01-2022 Through 23-01-2022",
year = "2022",
month = mar,
day = "3",
doi = "10.1117/12.2608663",
language = "English",
isbn = "978-1-5106-4739-8",
volume = "11934",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Bernard Choi and Haishan Zeng",
booktitle = "Photonics in Dermatology and Plastic Surgery 2022",
address = "United States",
}