Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

Antonie E. Ekkelenkamp; M. Rachèl Elzes; Johan F.J. Engbersen; Jos M.J. Paulusse

doi:10.1039/c7tb02239e

Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

Antonie E. Ekkelenkamp
, M. Rachèl Elzes
, Johan F.J. Engbersen
, Jos M.J. Paulusse^* (Corresponding Author)

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

104 Citations (Scopus)

238 Downloads (Pure)

Abstract

Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles, which have highly interesting properties for therapeutic delivery and imaging. Nanogels may also possess responsive properties, depending on the employed polymers, allowing controlled release of therapeutics or image contrast generation upon exposure to physical or (bio)chemical cues. In this review, polymer nanogels are explored for application in imaging as well as for controlled drug and gene delivery. Moreover, nanogels are explored as responsive biomaterials and future applications are highlighted.

Original language	English
Pages (from-to)	210-235
Number of pages	26
Journal	Journal of materials chemistry. B: materials for biology and medicine
Volume	6
Issue number	2
DOIs	https://doi.org/10.1039/c7tb02239e
Publication status	Published - 14 Jan 2018

Keywords

22/4 OA procedure

Access to Document

10.1039/c7tb02239e

ArticleFinal published version, 6.24 MBLicence: Taverne

Cite this

@article{c0a6dede045743d8966d576096e5018e,

title = "Responsive crosslinked polymer nanogels for imaging and therapeutics delivery",

abstract = "Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles, which have highly interesting properties for therapeutic delivery and imaging. Nanogels may also possess responsive properties, depending on the employed polymers, allowing controlled release of therapeutics or image contrast generation upon exposure to physical or (bio)chemical cues. In this review, polymer nanogels are explored for application in imaging as well as for controlled drug and gene delivery. Moreover, nanogels are explored as responsive biomaterials and future applications are highlighted.",

keywords = "22/4 OA procedure",

author = "Ekkelenkamp, \{Antonie E.\} and Elzes, \{M. Rach{\`e}l\} and Engbersen, \{Johan F.J.\} and Paulusse, \{Jos M.J.\}",

year = "2018",

month = jan,

day = "14",

doi = "10.1039/c7tb02239e",

language = "English",

volume = "6",

pages = "210--235",

journal = "Journal of materials chemistry. B: materials for biology and medicine",

issn = "2050-750X",

publisher = "Royal Society of Chemistry",

number = "2",

}

TY - JOUR

T1 - Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

AU - Ekkelenkamp, Antonie E.

AU - Elzes, M. Rachèl

AU - Engbersen, Johan F.J.

AU - Paulusse, Jos M.J.

PY - 2018/1/14

Y1 - 2018/1/14

N2 - Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles, which have highly interesting properties for therapeutic delivery and imaging. Nanogels may also possess responsive properties, depending on the employed polymers, allowing controlled release of therapeutics or image contrast generation upon exposure to physical or (bio)chemical cues. In this review, polymer nanogels are explored for application in imaging as well as for controlled drug and gene delivery. Moreover, nanogels are explored as responsive biomaterials and future applications are highlighted.

AB - Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles, which have highly interesting properties for therapeutic delivery and imaging. Nanogels may also possess responsive properties, depending on the employed polymers, allowing controlled release of therapeutics or image contrast generation upon exposure to physical or (bio)chemical cues. In this review, polymer nanogels are explored for application in imaging as well as for controlled drug and gene delivery. Moreover, nanogels are explored as responsive biomaterials and future applications are highlighted.

KW - 22/4 OA procedure

UR - https://www.scopus.com/pages/publications/85040188081

U2 - 10.1039/c7tb02239e

DO - 10.1039/c7tb02239e

M3 - Review article

AN - SCOPUS:85040188081

SN - 2050-750X

VL - 6

SP - 210

EP - 235

JO - Journal of materials chemistry. B: materials for biology and medicine

JF - Journal of materials chemistry. B: materials for biology and medicine

IS - 2

ER -

Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this