Review: Bioelectrical mechanisms in spinal cord stimulation

Jan Holsheimer; Jan R. Buitenweg

doi:10.1111/ner.12279

Review: Bioelectrical mechanisms in spinal cord stimulation

Jan Holsheimer^*
, Jan R. Buitenweg

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

49 Citations (Scopus)

180 Downloads (Pure)

Abstract

Objectives The aim of this review is to make specialists in a variety of disciplines familiar with basic aspects of spinal cord stimulation and the role of mathematical modeling in understanding its mechanisms of action and the solution of basic problems. Methods The paper is divided into five sections. The content of each section also covers aspects of various disciplines. Most aspects are presented in an unusual way, likely resulting in new viewpoints and further developments in the growing field of neuromodulation. Results A special, integrating role is the mathematical modeling of spinal cord stimulation and the simulation studies of various aspects, such as the stimulation in axial low-back pain. Conclusions In particular the conclusions from several computer simulation studies are relevant and of interest to specialists in many disciplines. © 2015 International Neuromodulation Society.

Original language	English
Pages (from-to)	161-170
Number of pages	10
Journal	Neuromodulation
Volume	18
Issue number	3
DOIs	https://doi.org/10.1111/ner.12279
Publication status	Published - 2015

Keywords

2024 OA procedure
Electrode paddle
Spinal cord stimulation
Stimulation
Review article
BSS-Central mechanisms underlying chronic pain
Electrode paddlelow back painreview articlespinal cord stimulationstimulationcell selectioncell sizecerebrospinal fluidclinical trial (topic)computer simulationcuneate fascicledermatomedual lead stimulationequipment designevoked somatosensory responsefinite element modelgracile fasciclehumanlaminectomy leadmathematical analysismathematical modelnerve fiber sortingnerve stimulatornerve tractneuromodulationneurophysiological recruitmentneurophysiologyparesthesiapercutaneous leadrandomized controlled trial (topic)Reviewsingle lead stimulationspinal cord dorsal hornspinal cord stimulatoranimalBack Painelectrode implantphysiologyproceduresspinal cordAnimalsElectrodes
ImplantedHumans
Low Back Pain (LBP)

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10.1111/ner.12279

ArticleFinal published version, 835 KBLicence: Taverne

Cite this

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author = "Jan Holsheimer and Buitenweg, \{Jan R.\}",

year = "2015",

doi = "10.1111/ner.12279",

language = "English",

volume = "18",

pages = "161--170",

journal = "Neuromodulation",

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publisher = "International Neuromodulation Society",

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AU - Buitenweg, Jan R.

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AB - Objectives The aim of this review is to make specialists in a variety of disciplines familiar with basic aspects of spinal cord stimulation and the role of mathematical modeling in understanding its mechanisms of action and the solution of basic problems. Methods The paper is divided into five sections. The content of each section also covers aspects of various disciplines. Most aspects are presented in an unusual way, likely resulting in new viewpoints and further developments in the growing field of neuromodulation. Results A special, integrating role is the mathematical modeling of spinal cord stimulation and the simulation studies of various aspects, such as the stimulation in axial low-back pain. Conclusions In particular the conclusions from several computer simulation studies are relevant and of interest to specialists in many disciplines. © 2015 International Neuromodulation Society.

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Review: Bioelectrical mechanisms in spinal cord stimulation

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Keywords

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