Rheumajecta and Vasolastine in the treatment of Rheumatoid arthritis: Results of a placebo-controlled, double-blind trial of a complementary treatment

J.W.G. Jacobs, J.J. Rasker, P.L.C.M. van Riel, F.W.J. Gribnau, L.B.A. van de Putte

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Abstract

The so called “enzymatic preparations” Rheumajecta and Vasolastine (R & V) belong to the complementary treatments. The preparations have been used for many years in the treatment of patients with rheumatic conditions such as rheumatoid arthritis (RA) in the Netherlands and other countries of Europe, although a proper study showing efficacy was never performed. Therefore a double-blind, placebo-controlled, modified cross-over trial during two periods of 3 months was performed in 34 patients with RA. They were allocated at random to R & V or to placebo injections, all intramuscular. After 3 months of therapy each patient could opt for cross-over in the event of lack of subjective improvement. Clinical assessments including Ritchie's articular index, grip strength, the DUTCH-AIMS questionnaire, ESR and CRP were performed. R & V did not prove to be more effective than placebo. No serious side-effects were seen.
Original languageEnglish
Pages (from-to)434-440
Number of pages7
JournalScandinavian journal of rheumatology
Volume20
Issue number6
DOIs
Publication statusPublished - 1991
Externally publishedYes

Keywords

  • Rheumajecta
  • Vasolastine
  • Enzymic preparations
  • Complementary medicine
  • DUTCH-AIMS

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